Projects per year
The synthesis of potent inhibitors of GH93 arabinanases as well as a synthesis of a chromogenic substrate to measure GH93 arabinanase activity are described. An insight into the reasons behind the potency of the inhibitors was gained through X-ray crystallographic analysis of the arabinanase Arb93A from Fusarium graminearum. These compounds lay a foundation for future inhibitor development as well as for the use of the chromogenic substrate in biochemical studies of GH93 arabinanases.
FingerprintDive into the research topics of 'Exploiting sp2-Hybridisation in the Development of Potent 1,5-α-l-Arabinanase Inhibitors'. Together they form a unique fingerprint.
- 2 Finished
1/01/14 → 28/02/18
1/01/10 → 30/06/15