Exhaled Nitric Oxide Is Reduced in Infants With Rhinorrhea

Peter Franklin; Graham Hall; Stephen Stick; S.W. Turner; A. Moeller

doi:10.1002/ppul.20149

Exhaled Nitric Oxide Is Reduced in Infants With Rhinorrhea

Peter Franklin, Graham Hall, Stephen Stick, S.W. Turner, A. Moeller

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

In infants, the effect of colds and other respiratory tract infections (RTI) on exhaled nitric oxide (FENO) is not clear In this study, we measured FENO in 24 infants (14 boys) who presented with rhinorrhea, with or without Cough but not wheeze. Twelve of these infants had a history of recurrent wheeze. Levels were compared with a group of 23 healthy infants (13 boys). Further, 8 infants (5 with a history of recurrent wheeze) with rhinorrhea were tested after symptoms had resolved. Infants with rhinorrhea had significantly lower FENO than the healthy infants (11.9vs. 23.8 ppb, respectively, P< 0.0007). Levels increased from 7.5 ppb to 34.1 ppb in the 8 infants tested with and without symptoms (P = 0.0002). Infants with rhinorrhea have reduced FENO, irrespective of their respiratory history.

Original language	English
Pages (from-to)	117-119
Journal	Pediatric Pulmonology
Volume	39
Issue number	2
DOIs	https://doi.org/10.1002/ppul.20149
Publication status	Published - 2005

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title = "Exhaled Nitric Oxide Is Reduced in Infants With Rhinorrhea",

abstract = "In infants, the effect of colds and other respiratory tract infections (RTI) on exhaled nitric oxide (FENO) is not clear In this study, we measured FENO in 24 infants (14 boys) who presented with rhinorrhea, with or without Cough but not wheeze. Twelve of these infants had a history of recurrent wheeze. Levels were compared with a group of 23 healthy infants (13 boys). Further, 8 infants (5 with a history of recurrent wheeze) with rhinorrhea were tested after symptoms had resolved. Infants with rhinorrhea had significantly lower FENO than the healthy infants (11.9vs. 23.8 ppb, respectively, P< 0.0007). Levels increased from 7.5 ppb to 34.1 ppb in the 8 infants tested with and without symptoms (P = 0.0002). Infants with rhinorrhea have reduced FENO, irrespective of their respiratory history.",

author = "Peter Franklin and Graham Hall and Stephen Stick and S.W. Turner and A. Moeller",

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T1 - Exhaled Nitric Oxide Is Reduced in Infants With Rhinorrhea

AU - Franklin, Peter

AU - Hall, Graham

AU - Stick, Stephen

AU - Turner, S.W.

AU - Moeller, A.

PY - 2005

Y1 - 2005

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AB - In infants, the effect of colds and other respiratory tract infections (RTI) on exhaled nitric oxide (FENO) is not clear In this study, we measured FENO in 24 infants (14 boys) who presented with rhinorrhea, with or without Cough but not wheeze. Twelve of these infants had a history of recurrent wheeze. Levels were compared with a group of 23 healthy infants (13 boys). Further, 8 infants (5 with a history of recurrent wheeze) with rhinorrhea were tested after symptoms had resolved. Infants with rhinorrhea had significantly lower FENO than the healthy infants (11.9vs. 23.8 ppb, respectively, P< 0.0007). Levels increased from 7.5 ppb to 34.1 ppb in the 8 infants tested with and without symptoms (P = 0.0002). Infants with rhinorrhea have reduced FENO, irrespective of their respiratory history.

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DO - 10.1002/ppul.20149

M3 - Article

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JO - Pediatric Pulmonology

JF - Pediatric Pulmonology

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ER -

Exhaled Nitric Oxide Is Reduced in Infants With Rhinorrhea

Abstract

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