TY - JOUR
T1 - Exercise training, vascular function and functional capacity in middle-aged subjects.
AU - Maiorana, A.
AU - O'Driscoll, Gerry
AU - Dembo, L.
AU - Goodman, Carmel
AU - Taylor, R.R.
AU - Green, Daniel
PY - 2001
Y1 - 2001
N2 - Purpose: The aim of this study Aas to investigate the effect of 8 wk of exercise training on functional capacity. muscular strength, body composition, and vascular function in sedentary but healthy subjects by using a randomized. crossover protocol, Methods: After familiarization sessions. 19 subjects aged 47 +/- 2 yr (mean : SE) undertook a randomized. crossover design study of the effect of 8 wk of supervised circuit training consisting of combined aerobic and resistance exercise. Peak oxygen uptake ((V) over dot O-2peak). sum of 7 maximal voluntary contractions and the sum of 8 skinfolds and 5 segment girths vv ere determined at entry, crossover. and 16 Ak. Endothelium-dependent and -independent vascular function were determined by forearm strain-gauge plethysmography and intrabrachial infusions of acetylcholine (ACh) and sodium nitroprusside (SNP) in 16 subjects. Results: Training did not alter ACh or SNP responses. (V) over dot O-2peak (28.6 +/- 1.1 to 32.6 +/- 1.3 mL(.)kg(-1.)mm(-1), P <0.001), exercise test duration (17.4 +/- 1.1 to 22.1 +/- 1.2 min, P <0.001), and muscular strength (465 +/- 27 to 535 +/- 27 kg, P
AB - Purpose: The aim of this study Aas to investigate the effect of 8 wk of exercise training on functional capacity. muscular strength, body composition, and vascular function in sedentary but healthy subjects by using a randomized. crossover protocol, Methods: After familiarization sessions. 19 subjects aged 47 +/- 2 yr (mean : SE) undertook a randomized. crossover design study of the effect of 8 wk of supervised circuit training consisting of combined aerobic and resistance exercise. Peak oxygen uptake ((V) over dot O-2peak). sum of 7 maximal voluntary contractions and the sum of 8 skinfolds and 5 segment girths vv ere determined at entry, crossover. and 16 Ak. Endothelium-dependent and -independent vascular function were determined by forearm strain-gauge plethysmography and intrabrachial infusions of acetylcholine (ACh) and sodium nitroprusside (SNP) in 16 subjects. Results: Training did not alter ACh or SNP responses. (V) over dot O-2peak (28.6 +/- 1.1 to 32.6 +/- 1.3 mL(.)kg(-1.)mm(-1), P <0.001), exercise test duration (17.4 +/- 1.1 to 22.1 +/- 1.2 min, P <0.001), and muscular strength (465 +/- 27 to 535 +/- 27 kg, P
U2 - 10.1097/00005768-200112000-00008
DO - 10.1097/00005768-200112000-00008
M3 - Article
SN - 0195-9131
VL - 33
SP - 2022
EP - 2028
JO - Medicine and Science in Sports and Exercise
JF - Medicine and Science in Sports and Exercise
ER -