TY - JOUR
T1 - Exercise and vascular function in child obesity: A meta-analysis
AU - Dias, K.A.
AU - Green, Daniel J
AU - Ingul, C.B.
AU - Pavey, T.G.
AU - Coombes, J.S.
PY - 2015
Y1 - 2015
N2 - © 2015 by the American Academy of Pediatrics. CONTEXT: Conduit artery flow-mediated dilation (FMD) is a noninvasive index of preclinical atherosclerosis in humans. Exercise interventions can improve FMD in both healthy and clinical populations. OBJECTIVE: This systematic review and meta-analysis aimed to summarize the effect of exercise training on FMD in overweight and obese children and adolescents as well as investigate the role of cardiorespiratory fitness (peak oxygen consumption [VO2peak]) on effects observed. DATA SOURCES: PubMed, Medline, Embase, and Cinahl databases were searched from the earliest available date to February 2015. STUDY SELECTION: Studies of children and/or adolescents who were overweight or obese were included. DATA EXTRACTION: Standardized data extraction forms were used for patient and intervention characteristics, control/comparator groups, and key outcomes. Procedural quality of the studies was assessed using a modified version of the Physiotherapy Evidence Base Database scale. RESULTS: A meta-analysis involving 219 participants compared the mean difference of preversus postintervention vascular function (FMD) and VO2peak between an exercise training intervention and a control condition. There was a significantly greater improvement in FMD (mean difference 1.54%, P 2peak (mean difference 3.64 mL/kg/min, P
AB - © 2015 by the American Academy of Pediatrics. CONTEXT: Conduit artery flow-mediated dilation (FMD) is a noninvasive index of preclinical atherosclerosis in humans. Exercise interventions can improve FMD in both healthy and clinical populations. OBJECTIVE: This systematic review and meta-analysis aimed to summarize the effect of exercise training on FMD in overweight and obese children and adolescents as well as investigate the role of cardiorespiratory fitness (peak oxygen consumption [VO2peak]) on effects observed. DATA SOURCES: PubMed, Medline, Embase, and Cinahl databases were searched from the earliest available date to February 2015. STUDY SELECTION: Studies of children and/or adolescents who were overweight or obese were included. DATA EXTRACTION: Standardized data extraction forms were used for patient and intervention characteristics, control/comparator groups, and key outcomes. Procedural quality of the studies was assessed using a modified version of the Physiotherapy Evidence Base Database scale. RESULTS: A meta-analysis involving 219 participants compared the mean difference of preversus postintervention vascular function (FMD) and VO2peak between an exercise training intervention and a control condition. There was a significantly greater improvement in FMD (mean difference 1.54%, P 2peak (mean difference 3.64 mL/kg/min, P
UR - https://www.scopus.com/pages/publications/84940868598
U2 - 10.1542/peds.2015-0616
DO - 10.1542/peds.2015-0616
M3 - Article
C2 - 26260721
SN - 0031-4005
VL - 136
SP - e648-e659
JO - Pediatrics
JF - Pediatrics
IS - 3
ER -
