Abstract
As men age, testosterone levels decline coinciding with increased risk of cardiovascular disease, reduced fitness and strength and unfavourable changes in body composition and cardiovascular health. This thesis describes two epidemiological analyses, providing evidence that the combination of higher testosterone levels and higher physical activity are associated with lower cardiovascular mortality risk. A subsequent randomised controlled trial demonstrated that, in men aged 50-70yrs with low-normal testosterone levels, 12-weeks of supervised exercise training resulted in greater improvement of aerobic fitness, body composition, strength, blood pressure and vascular function than 12-weeks of testosterone treatment, or their combination.
Original language | English |
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Qualification | Doctor of Philosophy |
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Award date | 15 Mar 2022 |
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Publication status | Unpublished - 2021 |