Excision of the Shigella Resistance Locus Pathogenicity Island in Shigella flexneri Is Stimulated by a Member of a New Subgroup of Recombination Directionality Factors

S.N. Luck; S.A. Turner; K. Rajakumar; B. Adler; Harry Sakellaris

doi:10.1128/JB.186.16.5551-5554.2004

Excision of the Shigella Resistance Locus Pathogenicity Island in Shigella flexneri Is Stimulated by a Member of a New Subgroup of Recombination Directionality Factors

S.N. Luck, S.A. Turner, K. Rajakumar, B. Adler, Harry Sakellaris

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Pathogenicity islands are capable of excision and insertion within bacterial chromosomes. We describe a protein, Rox, that stimulates excision of the Shigella resistance locus pathogenicity island in Shigella flexneri. Sequence analysis suggests that Rox belongs to a new subfamily of recombination directionality factors, which includes proteins from P4, enterohemorrhagic Escherichia coli, and Yersinia pestis.

Original language	English
Pages (from-to)	5551-5554
Journal	Journal of Bacteriology
Volume	186
Issue number	16
DOIs	https://doi.org/10.1128/JB.186.16.5551-5554.2004
Publication status	Published - 2004

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10.1128/JB.186.16.5551-5554.2004

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title = "Excision of the Shigella Resistance Locus Pathogenicity Island in Shigella flexneri Is Stimulated by a Member of a New Subgroup of Recombination Directionality Factors",

abstract = "Pathogenicity islands are capable of excision and insertion within bacterial chromosomes. We describe a protein, Rox, that stimulates excision of the Shigella resistance locus pathogenicity island in Shigella flexneri. Sequence analysis suggests that Rox belongs to a new subfamily of recombination directionality factors, which includes proteins from P4, enterohemorrhagic Escherichia coli, and Yersinia pestis.",

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AU - Luck, S.N.

AU - Turner, S.A.

AU - Rajakumar, K.

AU - Adler, B.

AU - Sakellaris, Harry

PY - 2004

Y1 - 2004

N2 - Pathogenicity islands are capable of excision and insertion within bacterial chromosomes. We describe a protein, Rox, that stimulates excision of the Shigella resistance locus pathogenicity island in Shigella flexneri. Sequence analysis suggests that Rox belongs to a new subfamily of recombination directionality factors, which includes proteins from P4, enterohemorrhagic Escherichia coli, and Yersinia pestis.

AB - Pathogenicity islands are capable of excision and insertion within bacterial chromosomes. We describe a protein, Rox, that stimulates excision of the Shigella resistance locus pathogenicity island in Shigella flexneri. Sequence analysis suggests that Rox belongs to a new subfamily of recombination directionality factors, which includes proteins from P4, enterohemorrhagic Escherichia coli, and Yersinia pestis.

U2 - 10.1128/JB.186.16.5551-5554.2004

DO - 10.1128/JB.186.16.5551-5554.2004

M3 - Article

VL - 186

SP - 5551

EP - 5554

JO - Journal of Bacteriology

JF - Journal of Bacteriology

SN - 0021-9193

IS - 16

ER -

Excision of the Shigella Resistance Locus Pathogenicity Island in Shigella flexneri Is Stimulated by a Member of a New Subgroup of Recombination Directionality Factors

Abstract

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