Excision of the Shigella Resistance Locus Pathogenicity Island in Shigella flexneri Is Stimulated by a Member of a New Subgroup of Recombination Directionality Factors

S.N. Luck, S.A. Turner, K. Rajakumar, B. Adler, Harry Sakellaris

    Research output: Contribution to journalArticlepeer-review

    16 Citations (Scopus)

    Abstract

    Pathogenicity islands are capable of excision and insertion within bacterial chromosomes. We describe a protein, Rox, that stimulates excision of the Shigella resistance locus pathogenicity island in Shigella flexneri. Sequence analysis suggests that Rox belongs to a new subfamily of recombination directionality factors, which includes proteins from P4, enterohemorrhagic Escherichia coli, and Yersinia pestis.
    Original languageEnglish
    Pages (from-to)5551-5554
    JournalJournal of Bacteriology
    Volume186
    Issue number16
    DOIs
    Publication statusPublished - 2004

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