Ex-vivo imaging of blood and lymphatic vessels in conjunctiva using optical coherence tomography

Peijun Gong, Karol Karnowski, Paula Yu, Dong An, Dao Yi Yu, David D. Sampson

Research output: Chapter in Book/Conference paperConference paperpeer-review

Abstract

Label-free imaging of the blood and lymphatic vessel networks of the conjunctiva of the eye is important in assessing the drainage pathways affected by glaucoma. We utilize the characteristically low signal in optical coherence tomography (OCT) provided by such vessels in ex vivo tissue to characterize their morphology in two and three dimensions. We demonstrate this method on conjunctiva from six porcine eyes, showing the ready visualization of both vessel networks. Such ex vivo characterization is a necessary precursor for future in vivo studies directed towards improving glaucoma surgery.

Original languageEnglish
Title of host publicationInternational Conference on Biophotonics V
EditorsJurgen Popp, Brian C. Wilson, David D. Sampson, Dennis L. Matthews, Halina Rubinsztein-Dunlop
PublisherSPIE
Edition5th
ISBN (Electronic)9781510611252
DOIs
Publication statusPublished - 29 Apr 2017
Event5th International Conference on Biophotonics, ICOB 2017 - Perth, Australia
Duration: 30 Apr 20171 May 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10340
ISSN (Print)1605-7422

Conference

Conference5th International Conference on Biophotonics, ICOB 2017
Country/TerritoryAustralia
CityPerth
Period30/04/171/05/17

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