Evaluation of the Cepheid® Xpert® C. difficile binary toxin (BT) diagnostic assay

Alan M. McGovern; Grace O. Androga; Peter Moono; Deirdre A. Collins; Niki F. Foster; Barbara J. Chang; Thomas V. Riley

doi:10.1016/j.anaerobe.2018.03.004

Evaluation of the Cepheid^® Xpert^® C. difficile binary toxin (BT) diagnostic assay

Alan M. McGovern, Grace O. Androga, Peter Moono, Deirdre A. Collins, Niki F. Foster, Barbara J. Chang, Thomas V. Riley

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Strains of Clostridium difficile producing only binary toxin (CDT) are found commonly in animals but not humans. However, human diagnostic tests rarely look for CDT. The Cepheid Xpert C. difficile BT assay detects CDT with equal sensitivity (≥92%) in human and animal faecal samples.

Original language	English
Pages (from-to)	12-16
Number of pages	5
Journal	Anaerobe
Volume	51
DOIs	https://doi.org/10.1016/j.anaerobe.2018.03.004
Publication status	Published - 1 Jun 2018

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10.1016/j.anaerobe.2018.03.004

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title = "Evaluation of the Cepheid{\textregistered} Xpert{\textregistered} C. difficile binary toxin (BT) diagnostic assay",

abstract = "Strains of Clostridium difficile producing only binary toxin (CDT) are found commonly in animals but not humans. However, human diagnostic tests rarely look for CDT. The Cepheid Xpert C. difficile BT assay detects CDT with equal sensitivity (≥92%) in human and animal faecal samples.",

keywords = "Binary toxin, CDT, Clostridium difficile infection, Diagnostics, Piglets",

author = "McGovern, {Alan M.} and Androga, {Grace O.} and Peter Moono and Collins, {Deirdre A.} and Foster, {Niki F.} and Chang, {Barbara J.} and Riley, {Thomas V.}",

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AU - McGovern, Alan M.

AU - Androga, Grace O.

AU - Moono, Peter

AU - Collins, Deirdre A.

AU - Foster, Niki F.

AU - Chang, Barbara J.

AU - Riley, Thomas V.

PY - 2018/6/1

Y1 - 2018/6/1

N2 - Strains of Clostridium difficile producing only binary toxin (CDT) are found commonly in animals but not humans. However, human diagnostic tests rarely look for CDT. The Cepheid Xpert C. difficile BT assay detects CDT with equal sensitivity (≥92%) in human and animal faecal samples.

AB - Strains of Clostridium difficile producing only binary toxin (CDT) are found commonly in animals but not humans. However, human diagnostic tests rarely look for CDT. The Cepheid Xpert C. difficile BT assay detects CDT with equal sensitivity (≥92%) in human and animal faecal samples.

KW - Binary toxin

KW - CDT

KW - Clostridium difficile infection

KW - Diagnostics

KW - Piglets

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DO - 10.1016/j.anaerobe.2018.03.004

M3 - Article

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JO - Anaerobe

JF - Anaerobe

ER -

Evaluation of the Cepheid^® Xpert^® C. difficile binary toxin (BT) diagnostic assay

Abstract

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