Evaluation of the Cepheid Xpert C. difficile/Epi and Meridian Bioscience illumigene C. difficile assays for detecting Clostridium difficile ribotype 033 strains

Grace Androga; Alan Mcgovern; Briony Elliott; Barbara Chang; Tim Perkins; Niki Foster; Thomas Riley

doi:10.1128/JCM.03297-14

Evaluation of the Cepheid Xpert C. difficile/Epi and Meridian Bioscience illumigene C. difficile assays for detecting Clostridium difficile ribotype 033 strains

Grace Androga, Alan Mcgovern, Briony Elliott, Barbara Chang, Tim Perkins, Niki Foster, Thomas Riley

Research output: Contribution to journal › Article › peer-review

17 Citations (Web of Science)

Abstract

Copyright © 2015, American Society for Microbiology. All Rights Reserved. Clostridium difficile PCR ribotype 033 (RT033) is found in the gastrointestinal tracts of production animals and, occasionally, humans. The illumigene C. difficile assay (Meridian Bioscience, Inc.) failed to detect any of 52 C. difficile RT033 isolates, while all strains signaled positive for the binary toxin genes but were reported as negative for C. difficile by the Xpert C. difficile/Epi assay (Cepheid).

Original language	English
Pages (from-to)	973-975
Journal	Journal of Clinical Microbiology
Volume	53
Issue number	3
DOIs	https://doi.org/10.1128/JCM.03297-14
Publication status	Published - 2015

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title = "Evaluation of the Cepheid Xpert C. difficile/Epi and Meridian Bioscience illumigene C. difficile assays for detecting Clostridium difficile ribotype 033 strains",

abstract = "Copyright {\textcopyright} 2015, American Society for Microbiology. All Rights Reserved. Clostridium difficile PCR ribotype 033 (RT033) is found in the gastrointestinal tracts of production animals and, occasionally, humans. The illumigene C. difficile assay (Meridian Bioscience, Inc.) failed to detect any of 52 C. difficile RT033 isolates, while all strains signaled positive for the binary toxin genes but were reported as negative for C. difficile by the Xpert C. difficile/Epi assay (Cepheid).",

author = "Grace Androga and Alan Mcgovern and Briony Elliott and Barbara Chang and Tim Perkins and Niki Foster and Thomas Riley",

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AU - Elliott, Briony

AU - Chang, Barbara

AU - Perkins, Tim

AU - Foster, Niki

AU - Riley, Thomas

PY - 2015

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N2 - Copyright © 2015, American Society for Microbiology. All Rights Reserved. Clostridium difficile PCR ribotype 033 (RT033) is found in the gastrointestinal tracts of production animals and, occasionally, humans. The illumigene C. difficile assay (Meridian Bioscience, Inc.) failed to detect any of 52 C. difficile RT033 isolates, while all strains signaled positive for the binary toxin genes but were reported as negative for C. difficile by the Xpert C. difficile/Epi assay (Cepheid).

AB - Copyright © 2015, American Society for Microbiology. All Rights Reserved. Clostridium difficile PCR ribotype 033 (RT033) is found in the gastrointestinal tracts of production animals and, occasionally, humans. The illumigene C. difficile assay (Meridian Bioscience, Inc.) failed to detect any of 52 C. difficile RT033 isolates, while all strains signaled positive for the binary toxin genes but were reported as negative for C. difficile by the Xpert C. difficile/Epi assay (Cepheid).

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DO - 10.1128/JCM.03297-14

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Evaluation of the Cepheid Xpert C. difficile/Epi and Meridian Bioscience illumigene C. difficile assays for detecting Clostridium difficile ribotype 033 strains

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