Evaluation of large-intestinal parameters associated with dietary treatments designed to reduce the occurrence of swine dysentery

Zoey Durmic, D.W. Pethick, B.P. Mullan, J.M. Accioly, H. Schulze, D.J. Hampson

    Research output: Contribution to journalArticle

    14 Citations (Scopus)

    Abstract

    Diets containing soluble NSP (sNSP) and resistant starch (RS) increase hindgut fermentation in pigs, which in turn increases the incidence of swine dysentery (SD) after infection with the intestinal spirochaete Brachyspira hyodysenteriae. In the present study pigs were fed diets based on either wheat or sorghum, fed either raw or treated by extrusion, and/or with the addition of dietary enzymes to reduce RS and/or sNSP content. The aim was to determine the effects of these treatments on pig performance, large intestinal fermentation and expression of SD. Weaned pigs (n 132) were fed experimental diets for 4 weeks, when half the pigs in each treatment group were euthanased and samples collected to assess the influence of the diet on hindgut fermentation. The remaining pigs then were infected with B. hyodysenteriae, and monitored for development of SD. In general, compared with pigs fed raw wheat, fermentation in all parts of the large intestine was reduced either by feeding raw sorghum-based diets, or by feeding diets that were extruded. The addition of enzymes that degrade RS or sNSP reduced fermentation only in the distal parts of the large intestine. The incidence of SD was lower in pigs fed sorghum-based diets, and some of the extruded diets, but none of the dietary treatments offered full protection against SD. Multiple regression analysis of the results from all three experiments showed that colonisation by spirochaetes was highly related to dietary sNSP concentrations, whilst development of SD was similarly influenced by RS content of the diet.
    Original languageEnglish
    Pages (from-to)159-169
    JournalBritish Journal of Nutrition
    Volume88
    DOIs
    Publication statusPublished - 2002

    Fingerprint Dive into the research topics of 'Evaluation of large-intestinal parameters associated with dietary treatments designed to reduce the occurrence of swine dysentery'. Together they form a unique fingerprint.

    Cite this