The Premier(TM) Clostridium difficile toxin A enzyme immunoassay (EIA) kit was evaluated for the detection of G. difficile enterotoxin in fecal samples. A total of 314 samples was tested by culture, cytotoxin detection and EIA kit. Compared to a combined culture/cytotoxin result the Premier(TM) EIA kit had a sensitivity of 88.3%, a specificity of 100%, a predictive value positive of 100% and a predictive value negative of 87.4%. Test results were available within 3 hrs providing a rapid and reliable means of detecting C. difficile enterotoxin.
Bowman, R. A., Arrow, S., Croese, L., & Riley, T. (1994). Evaluation of an enzyme immunoassay kit for the detection of Clostridium difficile enterotoxin. Pathology, 26, 480-481. https://doi.org/10.1080/00313029400169222