Evaluation of adherence to evidence-based pharmacotherapies from administrative health data in senior heart failure patients in Western Australia and associations with outcomes

Simon Qin

Research output: ThesisDoctoral Thesis

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Abstract

Evidence-based medications (EBM) have been shown to improve survival in patients with heart failure (HF). My study aimed to
assess long-term medication adherence to EBM in HF patients using the proportion of days covered (PDC) and associations
with outcomes. I showed that the PDC was a suitable adherence measure for administrative data. High adherence to EBMs
reduced the risk of death and composite of death and HF readmission. However, there was a declining trend in long-term
adherence following HF discharge. Targeted programs are needed for healthcare professionals, patients and family members to
optimise adherence to medications in patients with HF.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Award date12 Apr 2020
DOIs
Publication statusUnpublished - 2019

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