Abstract
Evidence-based medications (EBM) have been shown to improve survival in patients with heart failure (HF). My study aimed to
assess long-term medication adherence to EBM in HF patients using the proportion of days covered (PDC) and associations
with outcomes. I showed that the PDC was a suitable adherence measure for administrative data. High adherence to EBMs
reduced the risk of death and composite of death and HF readmission. However, there was a declining trend in long-term
adherence following HF discharge. Targeted programs are needed for healthcare professionals, patients and family members to
optimise adherence to medications in patients with HF.
assess long-term medication adherence to EBM in HF patients using the proportion of days covered (PDC) and associations
with outcomes. I showed that the PDC was a suitable adherence measure for administrative data. High adherence to EBMs
reduced the risk of death and composite of death and HF readmission. However, there was a declining trend in long-term
adherence following HF discharge. Targeted programs are needed for healthcare professionals, patients and family members to
optimise adherence to medications in patients with HF.
Original language | English |
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Qualification | Doctor of Philosophy |
Awarding Institution |
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Supervisors/Advisors |
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Award date | 12 Apr 2020 |
DOIs | |
Publication status | Unpublished - 2019 |