Evaluation of activity limitation in patients with idiopathic pulmonary fibrosis grouped according to medical research council dyspnea grade

R. Kozu, Sue Jenkins, H. Senjyu

    Research output: Contribution to journalArticle

    26 Citations (Scopus)

    Abstract

    Objective To investigate the relations between Medical Research Council (MRC) dyspnea grade and peripheral muscle force, activities of daily living (ADL) performance, health status, lung function, and exercise capacity in subjects with idiopathic pulmonary fibrosis (IPF). Design Prospective cross-sectional observational study. Setting University hospital. Participants Subjects with IPF (N=65, 46 men) in a stable clinical state with a mean age of 68±7 years. Interventions Not applicable. Main Outcome Measures Right ventricular systolic pressure (RVSP) via transthoracic echocardiography, pulmonary function, isometric quadriceps force (QF) and handgrip force (HF), 6-minute walk distance (6MWD), ADL score, and health status (Medical Outcomes Study 36-Item Short-Form Health Survey [SF-36]) were assessed and compared between subjects grouped according to MRC grade. Results Of the participants, 16 were in MRC grade 2, 17 were in MRC grade 3, 17 were in MRC grade 4, and 15 were in MRC grade 5. RVSP, pulmonary function, QF, HF, 6MWD, ADL, and SF-36 scores decreased with increasing MRC grade (all P.56, P=.001). Conclusions The MRC dyspnea scale provides a simple and useful method of categorizing individuals with IPF with respect to their activity limitation and may assist in understanding the impact of IPF on an individual. © 2014 by the American Congress of Rehabilitation Medicine.
    Original languageEnglish
    Pages (from-to)950-955
    JournalArchives of Physical Medicine and Rehabilitation
    Volume95
    Issue number5
    DOIs
    Publication statusPublished - 2014

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