Evaluation of a new commercially available immunoglobulin M capture enzyme-linked immunosorbent assay for diagnosis of dengue virus infection

M. Namekar, E.M. Ellis, M. O'Connell, J.L.S.B. Elm, A. Gurary, S.Y. Park, Allison Imrie, V.R. Nerurkar

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    Abstract

    We evaluated the FDA-cleared InBios dengue virus (DENV) IgM capture enzyme-linked immunosorbent assay (ELISA) for qualitative detection of anti-DENV IgM antibodies from 79 serum samples obtained from dengue virus-infected patients or suspected dengue cases. The agreement, sensitivity, and specificity of the InBios assay compared to the gold standard in-house DENV IgM capture ELISA were 94, 92, and 94%, respectively. We conclude that the InBios DENV IgM capture ELISA can be effectively used for rapid diagnosis of acute or recent DENV infection. Copyright © 2013, American Society for Microbiology. All Rights Reserved.
    Original languageEnglish
    Pages (from-to)3102-3106
    JournalJournal of Clinical Microbiology
    Volume51
    Issue number9
    DOIs
    Publication statusPublished - 2013

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