Estimating eligibility for lung cancer screening in an Australian cohort, including the effect of spirometry

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Abstract

Objectives: To estimate the proportion of ever-smokers who are eligible for lung cancer screening in an Australian cohort, and to evaluate the effect of spirometry in defining chronic obstructive pulmonary disease (COPD) when assessing screening eligibility. 

Design: Cross-sectional study of 3586 individuals aged 50–68 years who live in the Busselton Shire of Western Australia.

 Outcomes: Proportion of ever-smokers eligible for lung cancer screening based on United States Preventive Services Task Force (USPSTF) criteria, and PLCOm2012 lung cancer risk > 1.5%. The effect of using self-reported COPD, symptoms consistent with COPD, or spirometry to define COPD for screening eligibility according to the PLCOm2012 criteria. 

Results: Of ever-smokers aged 55–68 years, 254 (20.1%) would be eligible for screening according to USPSTF criteria; fewer would be eligible according to PLCOm2012 criteria (225, 17.9%; P = 0.004). This is equivalent to 8.9–10.0% of the total population aged 55–68 years, which suggests about 450 000 individuals in Australia may be eligible for lung cancer screening. The proportions of eligible participants were not significantly different whether spirometry results or symptoms consistent with COPD were used to determine PLCOm2012 risk. 

Conclusions: The proportion of ever-smokers in this population who were eligible for lung cancer screening was 17.9–20.1%. Using symptoms to define COPD is an appropriate surrogate measure for spirometry when determining the presence of COPD in this population. There are significant challenges for policy makers on how to identify and recruit these eligible individuals from the wider population.

Original languageEnglish
Pages (from-to)406.e1-406.e6
JournalMedical Journal of Australia
Volume204
Issue number11
DOIs
Publication statusPublished - 20 Jun 2016

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Cohort Effect
Spirometry
Early Detection of Cancer
Chronic Obstructive Pulmonary Disease
Lung Neoplasms
Advisory Committees
Population
Western Australia
Administrative Personnel
Cross-Sectional Studies

Cite this

@article{7544a080c5e949e5929954ef8b045e52,
title = "Estimating eligibility for lung cancer screening in an Australian cohort, including the effect of spirometry",
abstract = "Objectives: To estimate the proportion of ever-smokers who are eligible for lung cancer screening in an Australian cohort, and to evaluate the effect of spirometry in defining chronic obstructive pulmonary disease (COPD) when assessing screening eligibility. Design: Cross-sectional study of 3586 individuals aged 50–68 years who live in the Busselton Shire of Western Australia. Outcomes: Proportion of ever-smokers eligible for lung cancer screening based on United States Preventive Services Task Force (USPSTF) criteria, and PLCOm2012 lung cancer risk > 1.5{\%}. The effect of using self-reported COPD, symptoms consistent with COPD, or spirometry to define COPD for screening eligibility according to the PLCOm2012 criteria. Results: Of ever-smokers aged 55–68 years, 254 (20.1{\%}) would be eligible for screening according to USPSTF criteria; fewer would be eligible according to PLCOm2012 criteria (225, 17.9{\%}; P = 0.004). This is equivalent to 8.9–10.0{\%} of the total population aged 55–68 years, which suggests about 450 000 individuals in Australia may be eligible for lung cancer screening. The proportions of eligible participants were not significantly different whether spirometry results or symptoms consistent with COPD were used to determine PLCOm2012 risk. Conclusions: The proportion of ever-smokers in this population who were eligible for lung cancer screening was 17.9–20.1{\%}. Using symptoms to define COPD is an appropriate surrogate measure for spirometry when determining the presence of COPD in this population. There are significant challenges for policy makers on how to identify and recruit these eligible individuals from the wider population.",
author = "David Manners and Jennie Hui and Michael Hunter and Alan James and Knuiman, {Matthew W.} and Annette McWilliams and Siobhain Mulrennan and Musk, {Arthur W Bill} and Brims, {Fraser J H}",
year = "2016",
month = "6",
day = "20",
doi = "10.5694/mja16.00043",
language = "English",
volume = "204",
pages = "406.e1--406.e6",
journal = "Medical Journal Australia",
issn = "0025-729X",
publisher = "Australasian Medical Publishing Co. Ltd",
number = "11",

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TY - JOUR

T1 - Estimating eligibility for lung cancer screening in an Australian cohort, including the effect of spirometry

AU - Manners, David

AU - Hui, Jennie

AU - Hunter, Michael

AU - James, Alan

AU - Knuiman, Matthew W.

AU - McWilliams, Annette

AU - Mulrennan, Siobhain

AU - Musk, Arthur W Bill

AU - Brims, Fraser J H

PY - 2016/6/20

Y1 - 2016/6/20

N2 - Objectives: To estimate the proportion of ever-smokers who are eligible for lung cancer screening in an Australian cohort, and to evaluate the effect of spirometry in defining chronic obstructive pulmonary disease (COPD) when assessing screening eligibility. Design: Cross-sectional study of 3586 individuals aged 50–68 years who live in the Busselton Shire of Western Australia. Outcomes: Proportion of ever-smokers eligible for lung cancer screening based on United States Preventive Services Task Force (USPSTF) criteria, and PLCOm2012 lung cancer risk > 1.5%. The effect of using self-reported COPD, symptoms consistent with COPD, or spirometry to define COPD for screening eligibility according to the PLCOm2012 criteria. Results: Of ever-smokers aged 55–68 years, 254 (20.1%) would be eligible for screening according to USPSTF criteria; fewer would be eligible according to PLCOm2012 criteria (225, 17.9%; P = 0.004). This is equivalent to 8.9–10.0% of the total population aged 55–68 years, which suggests about 450 000 individuals in Australia may be eligible for lung cancer screening. The proportions of eligible participants were not significantly different whether spirometry results or symptoms consistent with COPD were used to determine PLCOm2012 risk. Conclusions: The proportion of ever-smokers in this population who were eligible for lung cancer screening was 17.9–20.1%. Using symptoms to define COPD is an appropriate surrogate measure for spirometry when determining the presence of COPD in this population. There are significant challenges for policy makers on how to identify and recruit these eligible individuals from the wider population.

AB - Objectives: To estimate the proportion of ever-smokers who are eligible for lung cancer screening in an Australian cohort, and to evaluate the effect of spirometry in defining chronic obstructive pulmonary disease (COPD) when assessing screening eligibility. Design: Cross-sectional study of 3586 individuals aged 50–68 years who live in the Busselton Shire of Western Australia. Outcomes: Proportion of ever-smokers eligible for lung cancer screening based on United States Preventive Services Task Force (USPSTF) criteria, and PLCOm2012 lung cancer risk > 1.5%. The effect of using self-reported COPD, symptoms consistent with COPD, or spirometry to define COPD for screening eligibility according to the PLCOm2012 criteria. Results: Of ever-smokers aged 55–68 years, 254 (20.1%) would be eligible for screening according to USPSTF criteria; fewer would be eligible according to PLCOm2012 criteria (225, 17.9%; P = 0.004). This is equivalent to 8.9–10.0% of the total population aged 55–68 years, which suggests about 450 000 individuals in Australia may be eligible for lung cancer screening. The proportions of eligible participants were not significantly different whether spirometry results or symptoms consistent with COPD were used to determine PLCOm2012 risk. Conclusions: The proportion of ever-smokers in this population who were eligible for lung cancer screening was 17.9–20.1%. Using symptoms to define COPD is an appropriate surrogate measure for spirometry when determining the presence of COPD in this population. There are significant challenges for policy makers on how to identify and recruit these eligible individuals from the wider population.

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U2 - 10.5694/mja16.00043

DO - 10.5694/mja16.00043

M3 - Article

VL - 204

SP - 406.e1-406.e6

JO - Medical Journal Australia

JF - Medical Journal Australia

SN - 0025-729X

IS - 11

ER -