TY - JOUR
T1 - Epidemiology and Clinical Features of Heart Failure with Preserved Ejection Fraction
AU - Teramoto, Kanako
AU - Teng, Tiew-Hwa Katherine
AU - Chandramouli, Chanchal
AU - Tromp, Jasper
AU - Sakata, Yasuhiko
AU - Lam, Carolyn Sp
PY - 2022
Y1 - 2022
N2 - Heart failure (HF) with preserved ejection (HFpEF) constitutes a large and growing proportion of patients with HF around the world, and is now responsible for more than half of all HF cases in ageing societies. While classically described as a condition of elderly, hypertensive women, recent studies suggest heterogeneity in clinical phenotypes involving differential characteristics and pathophysiological mechanisms. Despite a paucity of disease-modifying therapy for HFpEF, an understanding of phenotypic similarities and differences among patients with HFpEF around the world provides the foundation to recognise the clinical condition for early treatment, as well as to identify modifiable risk factors for preventive intervention. This review summarises the epidemiology of HFpEF, its common clinical features and risk factors, as well as differences by age, comorbidities, race/ethnicity and geography.
AB - Heart failure (HF) with preserved ejection (HFpEF) constitutes a large and growing proportion of patients with HF around the world, and is now responsible for more than half of all HF cases in ageing societies. While classically described as a condition of elderly, hypertensive women, recent studies suggest heterogeneity in clinical phenotypes involving differential characteristics and pathophysiological mechanisms. Despite a paucity of disease-modifying therapy for HFpEF, an understanding of phenotypic similarities and differences among patients with HFpEF around the world provides the foundation to recognise the clinical condition for early treatment, as well as to identify modifiable risk factors for preventive intervention. This review summarises the epidemiology of HFpEF, its common clinical features and risk factors, as well as differences by age, comorbidities, race/ethnicity and geography.
UR - http://www.scopus.com/inward/record.url?scp=85138630868&partnerID=8YFLogxK
U2 - 10.15420/cfr.2022.06
DO - 10.15420/cfr.2022.06
M3 - Review article
C2 - 35991117
SN - 2057-7540
VL - 8
JO - Cardiac Failure Review
JF - Cardiac Failure Review
M1 - e27
ER -