Engineering strategies to boost crop productivity by cutting respiratory carbon loss

Jeffrey S. Amthor, Arren Bar-Even, Andrew D. Hanson, A. Harvey Millar, Mark Stitt, Lee J. Sweetlove, Stephen D. Tyerman

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Roughly half the carbon that crop plants fix by photosynthesis is subsequently lost by respiration. Nonessential respiratory activity leading to unnecessary CO 2 release is unlikely to have been minimized by natural selection or crop breeding, and cutting this large loss could complement and reinforce the currently dominant yield-enhancement strategy of increasing carbon fixation. Until now, however, respiratory carbon losses have generally been overlooked by metabolic engineers and synthetic biologists because specific target genes have been elusive. We argue that recent advances are at last pinpointing individual enzyme and transporter genes that can be engineered to (1) slow unnecessary protein turnover, (2) replace, relocate, or reschedule metabolic activities, (3) suppress futile cycles, and (4) make ion transport more efficient, all of which can reduce respiratory costs. We identify a set of engineering strategies to reduce respiratory carbon loss that are now feasible and model how implementing these strategies singly or in tandem could lead to substantial gains in crop productivity.

Original languageEnglish
Pages (from-to)297-314
Number of pages18
JournalThe Plant Cell
Volume31
Issue number2
DOIs
Publication statusPublished - Feb 2019

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engineering
Carbon
carbon
crops
Substrate Cycling
Carbon Cycle
Genetic Selection
Ion Transport
Photosynthesis
ion transport
Carbon Monoxide
protein metabolism
plant breeding
engineers
Genes
natural selection
biologists
Breeding
transporters
Respiration

Cite this

Amthor, J. S., Bar-Even, A., Hanson, A. D., Millar, A. H., Stitt, M., Sweetlove, L. J., & Tyerman, S. D. (2019). Engineering strategies to boost crop productivity by cutting respiratory carbon loss. The Plant Cell, 31(2), 297-314. https://doi.org/10.1105/tpc.18.00743
Amthor, Jeffrey S. ; Bar-Even, Arren ; Hanson, Andrew D. ; Millar, A. Harvey ; Stitt, Mark ; Sweetlove, Lee J. ; Tyerman, Stephen D. / Engineering strategies to boost crop productivity by cutting respiratory carbon loss. In: The Plant Cell. 2019 ; Vol. 31, No. 2. pp. 297-314.
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Amthor, JS, Bar-Even, A, Hanson, AD, Millar, AH, Stitt, M, Sweetlove, LJ & Tyerman, SD 2019, 'Engineering strategies to boost crop productivity by cutting respiratory carbon loss' The Plant Cell, vol. 31, no. 2, pp. 297-314. https://doi.org/10.1105/tpc.18.00743

Engineering strategies to boost crop productivity by cutting respiratory carbon loss. / Amthor, Jeffrey S.; Bar-Even, Arren; Hanson, Andrew D.; Millar, A. Harvey; Stitt, Mark; Sweetlove, Lee J.; Tyerman, Stephen D.

In: The Plant Cell, Vol. 31, No. 2, 02.2019, p. 297-314.

Research output: Contribution to journalArticle

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