Engineering protein folding and interactions: Towards potential novel therapeutic interventions

Callum Fergus Ormonde

Research output: ThesisDoctoral Thesis

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Abstract

Protein engineering offers the potential to transform the pharmaceutical landscape through the development of biologically relevant drug systems. However controlling protein folding and delivery of therapeutic protein has been a major bottleneck. This PhD thesis describes approaches to dynamically control protein folding. deliver therapeutic proteins and study protein-DNA interactions using novel secondary DNA structures.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • Swaminatha Iyer, Iyer, Supervisor
  • Blancafort, Pilar, Supervisor
Award date18 Apr 2018
DOIs
Publication statusUnpublished - 2018

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