Engineering protein folding and interactions: Towards potential novel therapeutic interventions

Callum Fergus Ormonde

Research output: ThesisDoctoral Thesis

281 Downloads (Pure)

Abstract

Protein engineering offers the potential to transform the pharmaceutical landscape through the development of biologically relevant drug systems. However controlling protein folding and delivery of therapeutic protein has been a major bottleneck. This PhD thesis describes approaches to dynamically control protein folding. deliver therapeutic proteins and study protein-DNA interactions using novel secondary DNA structures.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • Swaminatha Iyer, Killugudi, Supervisor
  • Blancafort, Pilar, Supervisor
Award date18 Apr 2018
DOIs
Publication statusUnpublished - 2018

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