Endogenous factor VIII synthesis from the intron 22-inverted F8 locus may modulate the immunogenicity of replacement therapy for hemophilia A

G.S. Pandey; C. Yanover; L.M. Miller-Jenkins; S. Garfield; S.A. Cole; J.E. Curran; Eric Moses; N. Rydz; V. Simhadri; C. Kimchi-Sarfaty; D. Lillicrap; K.R. Viel; T.M. Przytycka; G.F. Pierce; T.E. Howard; Z.E. Sauna; J. Lusher; M. Chitlur; A. Ameri; K. Natarajan; R.V. Iyer; A.A. Thompson; R.G. Watts; C.L. Kempton; C. Kessler; J.C. Barrett; E.J. Martin; N. Key; R. Kruse-Jarres; C. Lessinger; K.P. Pratt; N. Josephson; K. Mcredmond; J. Withycombe; C. Walsh; D. Matthews; J. Mahlangu; A. Krause; R. Schwyzer; R. Thejpal; N. Rapiti; Y. Goga; M. Coetzee; D. Stones; K. Mann; S. Butenas; L. Almasy; J. Blangero; M. Carless; R. Raja; E. Reed

doi:10.1038/nm.3270

Endogenous factor VIII synthesis from the intron 22-inverted F8 locus may modulate the immunogenicity of replacement therapy for hemophilia A

G.S. Pandey, C. Yanover, L.M. Miller-Jenkins, S. Garfield, S.A. Cole, J.E. Curran, Eric Moses, N. Rydz, V. Simhadri, C. Kimchi-Sarfaty, D. Lillicrap, K.R. Viel, T.M. Przytycka, G.F. Pierce, T.E. Howard, Z.E. Sauna, J. Lusher, M. Chitlur, A. Ameri, K. NatarajanR.V. Iyer, A.A. Thompson, R.G. Watts, C.L. Kempton, C. Kessler, J.C. Barrett, E.J. Martin, N. Key, R. Kruse-Jarres, C. Lessinger, K.P. Pratt, N. Josephson, K. Mcredmond, J. Withycombe, C. Walsh, D. Matthews, J. Mahlangu, A. Krause, R. Schwyzer, R. Thejpal, N. Rapiti, Y. Goga, M. Coetzee, D. Stones, K. Mann, S. Butenas, L. Almasy, J. Blangero, M. Carless, R. Raja, E. Reed

Centre for Genetic Origins of Health and Diseases

Research output: Contribution to journal › Article › peer-review

60 Citations (Scopus)

Original language	English
Pages (from-to)	1318-24
Journal	Nature Medicine
Volume	19
Issue number	10
DOIs	https://doi.org/10.1038/nm.3270
Publication status	Published - 2013

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10.1038/nm.3270

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Pandey, G. S., Yanover, C., Miller-Jenkins, L. M., Garfield, S., Cole, S. A., Curran, J. E., Moses, E., Rydz, N., Simhadri, V., Kimchi-Sarfaty, C., Lillicrap, D., Viel, K. R., Przytycka, T. M., Pierce, G. F., Howard, T. E., Sauna, Z. E., Lusher, J., Chitlur, M., Ameri, A., ... Reed, E. (2013). Endogenous factor VIII synthesis from the intron 22-inverted F8 locus may modulate the immunogenicity of replacement therapy for hemophilia A. Nature Medicine, 19(10), 1318-24. https://doi.org/10.1038/nm.3270

@article{5072d8434ba344ac9b94a0112aa1355d,

title = "Endogenous factor VIII synthesis from the intron 22-inverted F8 locus may modulate the immunogenicity of replacement therapy for hemophilia A",

author = "G.S. Pandey and C. Yanover and L.M. Miller-Jenkins and S. Garfield and S.A. Cole and J.E. Curran and Eric Moses and N. Rydz and V. Simhadri and C. Kimchi-Sarfaty and D. Lillicrap and K.R. Viel and T.M. Przytycka and G.F. Pierce and T.E. Howard and Z.E. Sauna and J. Lusher and M. Chitlur and A. Ameri and K. Natarajan and R.V. Iyer and A.A. Thompson and R.G. Watts and C.L. Kempton and C. Kessler and J.C. Barrett and E.J. Martin and N. Key and R. Kruse-Jarres and C. Lessinger and K.P. Pratt and N. Josephson and K. Mcredmond and J. Withycombe and C. Walsh and D. Matthews and J. Mahlangu and A. Krause and R. Schwyzer and R. Thejpal and N. Rapiti and Y. Goga and M. Coetzee and D. Stones and K. Mann and S. Butenas and L. Almasy and J. Blangero and M. Carless and R. Raja and E. Reed",

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doi = "10.1038/nm.3270",

language = "English",

volume = "19",

pages = "1318--24",

journal = "Nature Medicine",

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Pandey, GS, Yanover, C, Miller-Jenkins, LM, Garfield, S, Cole, SA, Curran, JE, Moses, E, Rydz, N, Simhadri, V, Kimchi-Sarfaty, C, Lillicrap, D, Viel, KR, Przytycka, TM, Pierce, GF, Howard, TE, Sauna, ZE, Lusher, J, Chitlur, M, Ameri, A, Natarajan, K, Iyer, RV, Thompson, AA, Watts, RG, Kempton, CL, Kessler, C, Barrett, JC, Martin, EJ, Key, N, Kruse-Jarres, R, Lessinger, C, Pratt, KP, Josephson, N, Mcredmond, K, Withycombe, J, Walsh, C, Matthews, D, Mahlangu, J, Krause, A, Schwyzer, R, Thejpal, R, Rapiti, N, Goga, Y, Coetzee, M, Stones, D, Mann, K, Butenas, S, Almasy, L, Blangero, J, Carless, M, Raja, R & Reed, E 2013, 'Endogenous factor VIII synthesis from the intron 22-inverted F8 locus may modulate the immunogenicity of replacement therapy for hemophilia A', Nature Medicine, vol. 19, no. 10, pp. 1318-24. https://doi.org/10.1038/nm.3270

TY - JOUR

T1 - Endogenous factor VIII synthesis from the intron 22-inverted F8 locus may modulate the immunogenicity of replacement therapy for hemophilia A

AU - Pandey, G.S.

AU - Yanover, C.

AU - Miller-Jenkins, L.M.

AU - Garfield, S.

AU - Cole, S.A.

AU - Curran, J.E.

AU - Moses, Eric

AU - Rydz, N.

AU - Simhadri, V.

AU - Kimchi-Sarfaty, C.

AU - Lillicrap, D.

AU - Viel, K.R.

AU - Przytycka, T.M.

AU - Pierce, G.F.

AU - Howard, T.E.

AU - Sauna, Z.E.

AU - Lusher, J.

AU - Chitlur, M.

AU - Ameri, A.

AU - Natarajan, K.

AU - Iyer, R.V.

AU - Thompson, A.A.

AU - Watts, R.G.

AU - Kempton, C.L.

AU - Kessler, C.

AU - Barrett, J.C.

AU - Martin, E.J.

AU - Key, N.

AU - Kruse-Jarres, R.

AU - Lessinger, C.

AU - Pratt, K.P.

AU - Josephson, N.

AU - Mcredmond, K.

AU - Withycombe, J.

AU - Walsh, C.

AU - Matthews, D.

AU - Mahlangu, J.

AU - Krause, A.

AU - Schwyzer, R.

AU - Thejpal, R.

AU - Rapiti, N.

AU - Goga, Y.

AU - Coetzee, M.

AU - Stones, D.

AU - Mann, K.

AU - Butenas, S.

AU - Almasy, L.

AU - Blangero, J.

AU - Carless, M.

AU - Raja, R.

AU - Reed, E.

PY - 2013

Y1 - 2013

U2 - 10.1038/nm.3270

DO - 10.1038/nm.3270

M3 - Article

C2 - 24037092

SN - 1078-8956

VL - 19

SP - 1318

EP - 1324

JO - Nature Medicine

JF - Nature Medicine

IS - 10

ER -