Elucidating the link between Pneumonia and Cardiovascular Disease

Benjamin Bartlett

Research output: ThesisDoctoral Thesis

68 Downloads (Pure)

Abstract

Pneumonia, an inflammatory respiratory disease, has been associated with an increased risk of developing cardiovascular complications. While the exact mechanisms remain unknown, residual inflammation and microlesions are suspected of contributing to unstable plaque and compromised cardiac function respectively. By developing a dual disease murine model, I utilised a range of imaging (magnetic resonance imaging and positron emission tomography imaging), laboratory techniques (gene expression, histology and immunoassays) and mass spectrometry, to characterise the infection and investigate the effects on cardiovascular system. Altogether, my work created a platform which would help in understanding the role of pneumonia in causing adverse cardiac complications.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • Dwivedi, Girish, Supervisor
  • Waterer, Grant, Supervisor
  • Sanfilippo, Frank, Supervisor
  • Lee, Silvia, Supervisor
  • Ludewick, Herbert, Supervisor
Thesis sponsors
Award date19 May 2023
DOIs
Publication statusUnpublished - 2022

Fingerprint

Dive into the research topics of 'Elucidating the link between Pneumonia and Cardiovascular Disease'. Together they form a unique fingerprint.

Cite this