Elevated IGF1 in clinical opiate dependence

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    Abstract

    OBJECTIVE: To compare IGF1 levels in opiate dependent and general patients both absolutely and by age. DESIGN: A naturalistic observational study was undertaken of opiate dependent and general medical patients. SETTING: Primary care. PATIENTS: 74 opiate substance use dependent (SUD) patients were compared with 262 non-SUD (NSUD) patients. RESULTS: (1) Comparative IGF1 levels; (2) age and sex corrected IGF1 levels; (3) IGF1 levels corrected for age, sex, and hepatic and immune biomarkers. MAIN FINDINGS: The SUD patients were younger (32.60+0.89 vs. 42.49+0.96 years, mean+S.E.M., p
    Original languageEnglish
    Pages (from-to)18-26
    JournalNEUROENDOCRINOLOGY LETTERS
    Volume34
    Issue number1
    Publication statusPublished - 2013

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