Effects of loud tones on the inner ear: A combined electrophysiological and ultrastructural study

D. Robertson, B. M. Johnstone, T. J. McGill

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    Abstract

    Guinea pigs were exposed to a 10 kHz pure tone and damage to the cochlea was investigated immediately after exposure, or after a recovery period ranging from 18-25 days. Structural damage was assessed using scanning electron microscopy and functional damage estimated using the N1 threshold audiogram. Exposure at 106 dB for 1 h caused obvious abnormalities of outer hair cell stereocilia. The location and extent of this damage were related to the immediate or long term deficits in the N1 threshold audiogram.

    Original languageEnglish
    Pages (from-to)39-53
    Number of pages15
    JournalHearing Research
    Volume2
    Issue number1
    DOIs
    Publication statusPublished - 1 Jan 1980

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