Effects of high-intensity intermittent exercise training on appetite regulation

Aaron Sim, Karen Wallman, T.J. Fairchild, Kym Guelfi

Research output: Contribution to journalArticlepeer-review

58 Citations (Scopus)


© 2015 by the American College of Sports Medicine. Objective An acute bout of high-intensity intermittent exercise suppresses ad libitum energy intake at the postexercise meal. The present study examined the effects of 12 wk of high-intensity intermittent exercise training (HIIT) compared with moderate-intensity continuous exercise training (MICT) on appetite regulation. Methods Thirty overweight inactive men (body mass index, 27.2 ± 1.3 kg·m-2; VO2peak, 35.3 ± 5.3 mL·kg-1·min-1) were randomized to either HIIT or MICT (involving 12 wk of training, three sessions per week) or a control group (CON) (n = 10 per group). Ad libitum energy intake from a laboratory test meal was assessed after both a low-energy (847 kJ) and a high-energy preload (2438 kJ) before and after the intervention. Perceived appetite and appetite-related blood variables were also measured. Results There was no significant effect of the intervention period on energy intake at the test meal after the two different preloads (P ≥ 0.05). However, the 95% confidence interval indicated a clinically meaningful decrease in energy intake after the high-energy preload compared with the low-energy preload in response to HIIT (516 ± 395 kJ decrease), but not for MICT or CON, suggesting improved appetite regulation. This was not associated with alterations in the perception of appetite or the circulating concentration of a number of appetite-related peptides or metabolites, although insulin sensitivity was enhanced with HIIT only (P = 0.003). Conclusions HIIT seems to benefit appetite regulation in overweight men. The mechanisms for this remain to be elucidated.
Original languageEnglish
Pages (from-to)2441-2449
JournalMedicine and Science in Sports and Exercise
Issue number11
Publication statusPublished - 2015


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