Effectiveness of Different Commercial Chlorhexidine-Based Mouthwashes After Periodontal and Implant Surgery: A Systematic Review

Rachel Mei Ling Chye, Vittoria Perrotti, Adriano Piattelli, Flavia Iaculli, Alessandro Quaranta

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

OBJECTIVES: The aim of the present study was to review the effectiveness, side effects, and patient acceptance of different concentrations and formulation of chlorhexidine-based mouthwashes used after periodontal and implant surgery.

MATERIALS AND METHODS: The PRISMA guideline was adopted in the search strategy using electronic databases PubMed and MEDLINE to identify randomized and case-control prospective studies on humans written in English language and published up to September 2017.

RESULTS: A total of 10 articles were selected for a total of 344 patients. Because of the significant heterogeneity of the outcome measures, meta-analysis was not performed, and the data were summarized in a table. A positive relationship between the use of chlorhexidine and reduction of plaque was found, demonstrating the effectiveness of the substance in terms of antisepsis and decrease of inflammation after periodontal and implant surgery.

CONCLUSION: Chlorhexidine is recognized as the primary agent for plaque control and the gold standard in preventing infection, although the presence of largely known side effects would affect patient compliance. Future research should be directed at finding chlorhexidine formulation with negligible adverse effects, without compromising or even increasing its effectiveness as the antiseptics and antiplaque agent.

Original languageEnglish
Pages (from-to)74-85
Number of pages12
JournalImplant Dentistry
Volume28
Issue number1
DOIs
Publication statusPublished - Feb 2019

Fingerprint

Mouthwashes
Chlorhexidine
Antisepsis
Local Anti-Infective Agents
Patient Compliance
PubMed
MEDLINE
Meta-Analysis
Case-Control Studies
Language
Outcome Assessment (Health Care)
Databases
Prospective Studies
Guidelines
Inflammation
Infection

Cite this

Chye, Rachel Mei Ling ; Perrotti, Vittoria ; Piattelli, Adriano ; Iaculli, Flavia ; Quaranta, Alessandro. / Effectiveness of Different Commercial Chlorhexidine-Based Mouthwashes After Periodontal and Implant Surgery : A Systematic Review. In: Implant Dentistry. 2019 ; Vol. 28, No. 1. pp. 74-85.
@article{2995eeccbbf9493c891654301bae991f,
title = "Effectiveness of Different Commercial Chlorhexidine-Based Mouthwashes After Periodontal and Implant Surgery: A Systematic Review",
abstract = "OBJECTIVES: The aim of the present study was to review the effectiveness, side effects, and patient acceptance of different concentrations and formulation of chlorhexidine-based mouthwashes used after periodontal and implant surgery.MATERIALS AND METHODS: The PRISMA guideline was adopted in the search strategy using electronic databases PubMed and MEDLINE to identify randomized and case-control prospective studies on humans written in English language and published up to September 2017.RESULTS: A total of 10 articles were selected for a total of 344 patients. Because of the significant heterogeneity of the outcome measures, meta-analysis was not performed, and the data were summarized in a table. A positive relationship between the use of chlorhexidine and reduction of plaque was found, demonstrating the effectiveness of the substance in terms of antisepsis and decrease of inflammation after periodontal and implant surgery.CONCLUSION: Chlorhexidine is recognized as the primary agent for plaque control and the gold standard in preventing infection, although the presence of largely known side effects would affect patient compliance. Future research should be directed at finding chlorhexidine formulation with negligible adverse effects, without compromising or even increasing its effectiveness as the antiseptics and antiplaque agent.",
author = "Chye, {Rachel Mei Ling} and Vittoria Perrotti and Adriano Piattelli and Flavia Iaculli and Alessandro Quaranta",
year = "2019",
month = "2",
doi = "10.1097/ID.0000000000000854",
language = "English",
volume = "28",
pages = "74--85",
journal = "Implant Dentistry",
issn = "1056-6163",
publisher = "Lippincott Williams & Wilkins",
number = "1",

}

Effectiveness of Different Commercial Chlorhexidine-Based Mouthwashes After Periodontal and Implant Surgery : A Systematic Review. / Chye, Rachel Mei Ling; Perrotti, Vittoria; Piattelli, Adriano; Iaculli, Flavia; Quaranta, Alessandro.

In: Implant Dentistry, Vol. 28, No. 1, 02.2019, p. 74-85.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Effectiveness of Different Commercial Chlorhexidine-Based Mouthwashes After Periodontal and Implant Surgery

T2 - A Systematic Review

AU - Chye, Rachel Mei Ling

AU - Perrotti, Vittoria

AU - Piattelli, Adriano

AU - Iaculli, Flavia

AU - Quaranta, Alessandro

PY - 2019/2

Y1 - 2019/2

N2 - OBJECTIVES: The aim of the present study was to review the effectiveness, side effects, and patient acceptance of different concentrations and formulation of chlorhexidine-based mouthwashes used after periodontal and implant surgery.MATERIALS AND METHODS: The PRISMA guideline was adopted in the search strategy using electronic databases PubMed and MEDLINE to identify randomized and case-control prospective studies on humans written in English language and published up to September 2017.RESULTS: A total of 10 articles were selected for a total of 344 patients. Because of the significant heterogeneity of the outcome measures, meta-analysis was not performed, and the data were summarized in a table. A positive relationship between the use of chlorhexidine and reduction of plaque was found, demonstrating the effectiveness of the substance in terms of antisepsis and decrease of inflammation after periodontal and implant surgery.CONCLUSION: Chlorhexidine is recognized as the primary agent for plaque control and the gold standard in preventing infection, although the presence of largely known side effects would affect patient compliance. Future research should be directed at finding chlorhexidine formulation with negligible adverse effects, without compromising or even increasing its effectiveness as the antiseptics and antiplaque agent.

AB - OBJECTIVES: The aim of the present study was to review the effectiveness, side effects, and patient acceptance of different concentrations and formulation of chlorhexidine-based mouthwashes used after periodontal and implant surgery.MATERIALS AND METHODS: The PRISMA guideline was adopted in the search strategy using electronic databases PubMed and MEDLINE to identify randomized and case-control prospective studies on humans written in English language and published up to September 2017.RESULTS: A total of 10 articles were selected for a total of 344 patients. Because of the significant heterogeneity of the outcome measures, meta-analysis was not performed, and the data were summarized in a table. A positive relationship between the use of chlorhexidine and reduction of plaque was found, demonstrating the effectiveness of the substance in terms of antisepsis and decrease of inflammation after periodontal and implant surgery.CONCLUSION: Chlorhexidine is recognized as the primary agent for plaque control and the gold standard in preventing infection, although the presence of largely known side effects would affect patient compliance. Future research should be directed at finding chlorhexidine formulation with negligible adverse effects, without compromising or even increasing its effectiveness as the antiseptics and antiplaque agent.

U2 - 10.1097/ID.0000000000000854

DO - 10.1097/ID.0000000000000854

M3 - Article

VL - 28

SP - 74

EP - 85

JO - Implant Dentistry

JF - Implant Dentistry

SN - 1056-6163

IS - 1

ER -