A global epidemic of childhood obesity is projected to increase adult cardiovascular risk within the next generation. Animal studies suggest omega-3 fatty acids in pregnancy and infancy protect against cardiovascular risk in the offspring. However, few studies have examined whether this is true In humans. We hypothesised that supplementation during pregnancy or infancy would program improvements in blood pressure, blood lipids, mediators of inflammation and oxidative stress, and DNA telomeres. We showed omega-3 fatty acids were beneficial in the offspring Immediately following supplementation but there were no long-term benefits. These data provide a platform for future large-scale randomised controlled trials.
|Qualification||Doctor of Philosophy|
|Award date||9 May 2017|
|Publication status||Unpublished - 2017|