Effect of hepatitis C infection on the quality of life

Gergely Horváth, Teodóra Keleti, Mihály Makara, Gabor S. Ungvari, Gábor Gazdag

Research output: Contribution to journalArticle


Purpose: To assess the quality of life (QoL) of patients with hepatitis C infection (HCI) and its correlations with demographic and clinical variables. Design and Methods: QoL and depressive symptoms were evaluated with the validated rating instruments of the 36-item short form (SF-36) generic health survey and the second version of the self-rated Beck depression inventory (BDI-II) in a cross-sectional design and correlated with basic demographic and clinical variables, including the Fibroscan score, which indicates the severity of liver impairment. Findings: A cohort of 60 HCI patients who participated in the study scored lower than the general population on all domains of the SF-36. In the multivariate correlation analysis, only the physical functioning domain of the SF-36 showed a significant correlation with age, gender, and BD-II and Fibroscan scores. Implications for Clinical Practice: QoL is lower for patients who are older, female, and have depressive symptoms. Progression of hepatic cirrhosis is associated with lower QoL in the physical domain.

Original languageEnglish
Pages (from-to)386-390
Number of pages5
JournalPerspectives in Psychiatric Care
Issue number3
Publication statusPublished - 1 Jul 2018


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