Effect of combination therapy on arterial function in statin-treated type 2 diabetic patients

Sandy Hamilton

    Research output: ThesisDoctoral Thesis

    358 Downloads (Pure)

    Abstract

    [Truncated abstract] Type 2 diabetes mellitus (T2DM) markedly increases the risk of all forms of cardiovascular disease (CVD). Arterial dysfunction is an early feature and predictor of diabetic vascular disease and is causally related to diabetic dyslipidaemia. Statins, recommended as first-line therapy for diabetic dyslipidaemia, decrease CVD events principally by reducing LDL particle concentrations. However, their vascular benefits may be attenuated by inhibition of coenzyme Q10 (CoQ10) production. Therapeutic guidelines recommend LDL-cholesterol be lowered to a target goal of
    Original languageEnglish
    QualificationDoctor of Philosophy
    Publication statusUnpublished - 2011

    Fingerprint

    Dive into the research topics of 'Effect of combination therapy on arterial function in statin-treated type 2 diabetic patients'. Together they form a unique fingerprint.

    Cite this