Eccentric cycling: A promising modality for patients with chronic heart failure

L.C. C. Chasland, Daniel J. Green, A.J. J. Maoirana, K. Nosaka, Andy Haynes, L. Dembo, Louise H. Naylor

    Research output: Contribution to journalArticle

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    Abstract

    Purpose: Chronic heart failure (CHF) is characterized by dyspnea and poor exercise tolerance, which decreases aerobic capacity (VO2peak), a measure strongly correlated with quality of life and mortality. In healthy populations, eccentric (ECC) cycling can be performed at a lower oxygen demand for matched workload, compared with concentric (CON) cycling, but few studies have previously investigated ECC cycling in CHF. We hypothesized that, when matched for external workload (W), an ECC cycling bout would be performed at a lower cardiorespiratory load (VO2) than CON in patients with CHF. Methods: Eleven CHF patients (10 males) with impaired left ventricular systolic function (ejection fraction 31% ± 12%) completed a CON VO2peak test, with the subsequent ECC and CON protocols set at 70% of individual maximal CON power (W). Oxygen consumption (VO2), RER, minute ventilation (VE), HR, and rate pressure product were compared between conditions. Results: ECC was performed at a lower VO2 (12.3 ± 1.3 vs 14.1 ± 0.8 mL kg-1 min-1, P = 0.01), RER (0.92 ± 0.02 vs 0.96 ± 0.01, P = 0.01), and VE (36.5 ± 4.4 vs 40.2 ± 2.0 L min-1, P = 0.04) in comparison with CON, despite both conditions being performed at matched workloads. HR (101 ± 5 vs 96 ± 1 bpm, P = 0.06) and rate pressure product (13,539 ± 788 vs 11,911 ± 227 bpmImm Hg-1, P = 0.15) were not significantly different between conditions. Conclusion: When matched for external workload, ECC cycling can be performed with a lower oxygen demand than CON in patients with CHF. Eccentric cycling is a promising modality for cardiac rehabilitation in severely deconditioned patients with CHF Copyright © 2016 by the American College of Sports Medicine.
    Original languageEnglish
    Pages (from-to)646-651
    JournalMedicine and Science in Sports and Exercise
    Volume49
    Issue number4
    DOIs
    Publication statusPublished - 2017

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    Heart Failure
    Workload
    Ventilation
    Oxygen
    Pressure
    Exercise Tolerance
    Left Ventricular Function
    Oxygen Consumption
    Dyspnea
    Quality of Life
    Mortality
    Population

    Cite this

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    title = "Eccentric cycling: A promising modality for patients with chronic heart failure",
    abstract = "Purpose: Chronic heart failure (CHF) is characterized by dyspnea and poor exercise tolerance, which decreases aerobic capacity (VO2peak), a measure strongly correlated with quality of life and mortality. In healthy populations, eccentric (ECC) cycling can be performed at a lower oxygen demand for matched workload, compared with concentric (CON) cycling, but few studies have previously investigated ECC cycling in CHF. We hypothesized that, when matched for external workload (W), an ECC cycling bout would be performed at a lower cardiorespiratory load (VO2) than CON in patients with CHF. Methods: Eleven CHF patients (10 males) with impaired left ventricular systolic function (ejection fraction 31{\%} ± 12{\%}) completed a CON VO2peak test, with the subsequent ECC and CON protocols set at 70{\%} of individual maximal CON power (W). Oxygen consumption (VO2), RER, minute ventilation (VE), HR, and rate pressure product were compared between conditions. Results: ECC was performed at a lower VO2 (12.3 ± 1.3 vs 14.1 ± 0.8 mL kg-1 min-1, P = 0.01), RER (0.92 ± 0.02 vs 0.96 ± 0.01, P = 0.01), and VE (36.5 ± 4.4 vs 40.2 ± 2.0 L min-1, P = 0.04) in comparison with CON, despite both conditions being performed at matched workloads. HR (101 ± 5 vs 96 ± 1 bpm, P = 0.06) and rate pressure product (13,539 ± 788 vs 11,911 ± 227 bpmImm Hg-1, P = 0.15) were not significantly different between conditions. Conclusion: When matched for external workload, ECC cycling can be performed with a lower oxygen demand than CON in patients with CHF. Eccentric cycling is a promising modality for cardiac rehabilitation in severely deconditioned patients with CHF Copyright {\circledC} 2016 by the American College of Sports Medicine.",
    author = "Chasland, {L.C. C.} and Green, {Daniel J.} and Maoirana, {A.J. J.} and K. Nosaka and Andy Haynes and L. Dembo and Naylor, {Louise H.}",
    year = "2017",
    doi = "10.1249/MSS.0000000000001151",
    language = "English",
    volume = "49",
    pages = "646--651",
    journal = "Medicine & Science in Sports & Exercise",
    issn = "0195-9131",
    publisher = "Lippincott Williams & Wilkins",
    number = "4",

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    Eccentric cycling : A promising modality for patients with chronic heart failure. / Chasland, L.C. C.; Green, Daniel J.; Maoirana, A.J. J.; Nosaka, K.; Haynes, Andy; Dembo, L.; Naylor, Louise H.

    In: Medicine and Science in Sports and Exercise, Vol. 49, No. 4, 2017, p. 646-651.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Eccentric cycling

    T2 - A promising modality for patients with chronic heart failure

    AU - Chasland, L.C. C.

    AU - Green, Daniel J.

    AU - Maoirana, A.J. J.

    AU - Nosaka, K.

    AU - Haynes, Andy

    AU - Dembo, L.

    AU - Naylor, Louise H.

    PY - 2017

    Y1 - 2017

    N2 - Purpose: Chronic heart failure (CHF) is characterized by dyspnea and poor exercise tolerance, which decreases aerobic capacity (VO2peak), a measure strongly correlated with quality of life and mortality. In healthy populations, eccentric (ECC) cycling can be performed at a lower oxygen demand for matched workload, compared with concentric (CON) cycling, but few studies have previously investigated ECC cycling in CHF. We hypothesized that, when matched for external workload (W), an ECC cycling bout would be performed at a lower cardiorespiratory load (VO2) than CON in patients with CHF. Methods: Eleven CHF patients (10 males) with impaired left ventricular systolic function (ejection fraction 31% ± 12%) completed a CON VO2peak test, with the subsequent ECC and CON protocols set at 70% of individual maximal CON power (W). Oxygen consumption (VO2), RER, minute ventilation (VE), HR, and rate pressure product were compared between conditions. Results: ECC was performed at a lower VO2 (12.3 ± 1.3 vs 14.1 ± 0.8 mL kg-1 min-1, P = 0.01), RER (0.92 ± 0.02 vs 0.96 ± 0.01, P = 0.01), and VE (36.5 ± 4.4 vs 40.2 ± 2.0 L min-1, P = 0.04) in comparison with CON, despite both conditions being performed at matched workloads. HR (101 ± 5 vs 96 ± 1 bpm, P = 0.06) and rate pressure product (13,539 ± 788 vs 11,911 ± 227 bpmImm Hg-1, P = 0.15) were not significantly different between conditions. Conclusion: When matched for external workload, ECC cycling can be performed with a lower oxygen demand than CON in patients with CHF. Eccentric cycling is a promising modality for cardiac rehabilitation in severely deconditioned patients with CHF Copyright © 2016 by the American College of Sports Medicine.

    AB - Purpose: Chronic heart failure (CHF) is characterized by dyspnea and poor exercise tolerance, which decreases aerobic capacity (VO2peak), a measure strongly correlated with quality of life and mortality. In healthy populations, eccentric (ECC) cycling can be performed at a lower oxygen demand for matched workload, compared with concentric (CON) cycling, but few studies have previously investigated ECC cycling in CHF. We hypothesized that, when matched for external workload (W), an ECC cycling bout would be performed at a lower cardiorespiratory load (VO2) than CON in patients with CHF. Methods: Eleven CHF patients (10 males) with impaired left ventricular systolic function (ejection fraction 31% ± 12%) completed a CON VO2peak test, with the subsequent ECC and CON protocols set at 70% of individual maximal CON power (W). Oxygen consumption (VO2), RER, minute ventilation (VE), HR, and rate pressure product were compared between conditions. Results: ECC was performed at a lower VO2 (12.3 ± 1.3 vs 14.1 ± 0.8 mL kg-1 min-1, P = 0.01), RER (0.92 ± 0.02 vs 0.96 ± 0.01, P = 0.01), and VE (36.5 ± 4.4 vs 40.2 ± 2.0 L min-1, P = 0.04) in comparison with CON, despite both conditions being performed at matched workloads. HR (101 ± 5 vs 96 ± 1 bpm, P = 0.06) and rate pressure product (13,539 ± 788 vs 11,911 ± 227 bpmImm Hg-1, P = 0.15) were not significantly different between conditions. Conclusion: When matched for external workload, ECC cycling can be performed with a lower oxygen demand than CON in patients with CHF. Eccentric cycling is a promising modality for cardiac rehabilitation in severely deconditioned patients with CHF Copyright © 2016 by the American College of Sports Medicine.

    U2 - 10.1249/MSS.0000000000001151

    DO - 10.1249/MSS.0000000000001151

    M3 - Article

    VL - 49

    SP - 646

    EP - 651

    JO - Medicine & Science in Sports & Exercise

    JF - Medicine & Science in Sports & Exercise

    SN - 0195-9131

    IS - 4

    ER -