Duration of diabetes and its association with depression in later life: The Health in Men Study (HIMS)

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

© 2016 Elsevier Ireland Ltd. All rights reserved. Objective To examine if diabetes and duration of diabetes are direct or indirect causes of depression in later life. Research design and methods Cross-sectional study of a community-derived sample of 5462 men aged 70-89 years. Men with 'current depression' scored 7 or more on the abbreviated Geriatric Depression Scale (GDS-15), whereas men with 'ever depression' were either currently depressed or reported history or treatment for past depression. The presence of diabetes was established by self-reported history, fasting glucose =7 mmol/L (126 mg/dL), or use of insulin or hypoglycemic drugs. Duration of diabetes relied on self-report. Other measured factors included age, place of birth, education, smoking history, and the FRAIL scale. Results Diabetes was associated with increased odds ratio (OR) of ever (OR = 1.49, 95%CI = 1.25, 1.76) and current depression (OR = 1.94, 95%CI = 1.15, 2.48). The association between duration of diabetes and risk of current depression was 'J-shaped' with odds ratios of 1.92 (95%CI = 1.44, 2.54), 1.56 (95%CI = 0.89, 2.75), 2.49 (95%CI = 1.16, 5.32) and 3.13 (95%CI = 1.28, 7.63) for
Original languageEnglish
Pages (from-to)3-9
Number of pages7
JournalMaturitas
Volume86
Early online date11 Jan 2016
DOIs
Publication statusPublished - Apr 2016

Fingerprint

Men's Health
Medical problems
Health
Depression
Odds Ratio
History
Geriatrics
Hypoglycemic Agents
Age Factors
Ireland
Self Report
Education
Fasting
Insulin
Research Design
Cross-Sectional Studies
Smoking
Glucose

Cite this

@article{3d0e6d3a5b184c948d0483d0ec6cc805,
title = "Duration of diabetes and its association with depression in later life: The Health in Men Study (HIMS)",
abstract = "{\circledC} 2016 Elsevier Ireland Ltd. All rights reserved. Objective To examine if diabetes and duration of diabetes are direct or indirect causes of depression in later life. Research design and methods Cross-sectional study of a community-derived sample of 5462 men aged 70-89 years. Men with 'current depression' scored 7 or more on the abbreviated Geriatric Depression Scale (GDS-15), whereas men with 'ever depression' were either currently depressed or reported history or treatment for past depression. The presence of diabetes was established by self-reported history, fasting glucose =7 mmol/L (126 mg/dL), or use of insulin or hypoglycemic drugs. Duration of diabetes relied on self-report. Other measured factors included age, place of birth, education, smoking history, and the FRAIL scale. Results Diabetes was associated with increased odds ratio (OR) of ever (OR = 1.49, 95{\%}CI = 1.25, 1.76) and current depression (OR = 1.94, 95{\%}CI = 1.15, 2.48). The association between duration of diabetes and risk of current depression was 'J-shaped' with odds ratios of 1.92 (95{\%}CI = 1.44, 2.54), 1.56 (95{\%}CI = 0.89, 2.75), 2.49 (95{\%}CI = 1.16, 5.32) and 3.13 (95{\%}CI = 1.28, 7.63) for",
author = "Osvaldo Almeida and Kieran Mccaul and Graeme Hankey and Bu Yeap and J. Golledge and Paul Norman and Leon Flicker",
year = "2016",
month = "4",
doi = "10.1016/j.maturitas.2016.01.003",
language = "English",
volume = "86",
pages = "3--9",
journal = "Maturitas",
issn = "0378-5122",
publisher = "Elsevier",

}

TY - JOUR

T1 - Duration of diabetes and its association with depression in later life: The Health in Men Study (HIMS)

AU - Almeida, Osvaldo

AU - Mccaul, Kieran

AU - Hankey, Graeme

AU - Yeap, Bu

AU - Golledge, J.

AU - Norman, Paul

AU - Flicker, Leon

PY - 2016/4

Y1 - 2016/4

N2 - © 2016 Elsevier Ireland Ltd. All rights reserved. Objective To examine if diabetes and duration of diabetes are direct or indirect causes of depression in later life. Research design and methods Cross-sectional study of a community-derived sample of 5462 men aged 70-89 years. Men with 'current depression' scored 7 or more on the abbreviated Geriatric Depression Scale (GDS-15), whereas men with 'ever depression' were either currently depressed or reported history or treatment for past depression. The presence of diabetes was established by self-reported history, fasting glucose =7 mmol/L (126 mg/dL), or use of insulin or hypoglycemic drugs. Duration of diabetes relied on self-report. Other measured factors included age, place of birth, education, smoking history, and the FRAIL scale. Results Diabetes was associated with increased odds ratio (OR) of ever (OR = 1.49, 95%CI = 1.25, 1.76) and current depression (OR = 1.94, 95%CI = 1.15, 2.48). The association between duration of diabetes and risk of current depression was 'J-shaped' with odds ratios of 1.92 (95%CI = 1.44, 2.54), 1.56 (95%CI = 0.89, 2.75), 2.49 (95%CI = 1.16, 5.32) and 3.13 (95%CI = 1.28, 7.63) for

AB - © 2016 Elsevier Ireland Ltd. All rights reserved. Objective To examine if diabetes and duration of diabetes are direct or indirect causes of depression in later life. Research design and methods Cross-sectional study of a community-derived sample of 5462 men aged 70-89 years. Men with 'current depression' scored 7 or more on the abbreviated Geriatric Depression Scale (GDS-15), whereas men with 'ever depression' were either currently depressed or reported history or treatment for past depression. The presence of diabetes was established by self-reported history, fasting glucose =7 mmol/L (126 mg/dL), or use of insulin or hypoglycemic drugs. Duration of diabetes relied on self-report. Other measured factors included age, place of birth, education, smoking history, and the FRAIL scale. Results Diabetes was associated with increased odds ratio (OR) of ever (OR = 1.49, 95%CI = 1.25, 1.76) and current depression (OR = 1.94, 95%CI = 1.15, 2.48). The association between duration of diabetes and risk of current depression was 'J-shaped' with odds ratios of 1.92 (95%CI = 1.44, 2.54), 1.56 (95%CI = 0.89, 2.75), 2.49 (95%CI = 1.16, 5.32) and 3.13 (95%CI = 1.28, 7.63) for

U2 - 10.1016/j.maturitas.2016.01.003

DO - 10.1016/j.maturitas.2016.01.003

M3 - Article

VL - 86

SP - 3

EP - 9

JO - Maturitas

JF - Maturitas

SN - 0378-5122

ER -