Dual-Modality Confocal Laser Feedback Tomography for Highly Scattering Medium

Alireza Mowla, Karl Bertling, Stephen J. Wilson, Aleksandar D. Rakić

Research output: Contribution to journalArticle

Abstract

The combination of optical modalities is a common practice to improve the efficiency of biomedical optics systems. We propose confocal laser feedback tomography for volumetric dual-modality imaging. Two major modalities of laser Doppler flowmetry and reflectance confocal microscopy were integrated, and the signals were concurrently acquired for cross-sectional and volumetric imaging, by means of a compact laser scanning system. The technique was applied to a two-layered skin tissue phantom containing a 200- μm-diameter intralipid flow channel that features functional and morphological changes at the same time. Results show the potential for concurrent 3-D mapping of dynamic and static inhomogeneities in a highly scattering medium which can improve the contrast in non-invasive biological tissue imaging, providing a confocal image in addition to the Doppler flowmetry image.

Original languageEnglish
Article number8685137
Pages (from-to)6134-6140
Number of pages7
JournalIEEE Sensors Journal
Volume19
Issue number15
DOIs
Publication statusPublished - 1 Aug 2019

Fingerprint

Tomography
tomography
Scattering
Feedback
Imaging techniques
Lasers
scattering
Tissue
lasers
Confocal microscopy
channel flow
Channel flow
Skin
inhomogeneity
optics
microscopy
Scanning
reflectance
scanning
Biomedical optics

Cite this

Mowla, Alireza ; Bertling, Karl ; Wilson, Stephen J. ; Rakić, Aleksandar D. / Dual-Modality Confocal Laser Feedback Tomography for Highly Scattering Medium. In: IEEE Sensors Journal. 2019 ; Vol. 19, No. 15. pp. 6134-6140.
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Dual-Modality Confocal Laser Feedback Tomography for Highly Scattering Medium. / Mowla, Alireza; Bertling, Karl; Wilson, Stephen J.; Rakić, Aleksandar D.

In: IEEE Sensors Journal, Vol. 19, No. 15, 8685137, 01.08.2019, p. 6134-6140.

Research output: Contribution to journalArticle

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