Dual-Modality Confocal Laser Feedback Tomography for Highly Scattering Medium

Alireza Mowla, Karl Bertling, Stephen J. Wilson, Aleksandar D. Rakić

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


The combination of optical modalities is a common practice to improve the efficiency of biomedical optics systems. We propose confocal laser feedback tomography for volumetric dual-modality imaging. Two major modalities of laser Doppler flowmetry and reflectance confocal microscopy were integrated, and the signals were concurrently acquired for cross-sectional and volumetric imaging, by means of a compact laser scanning system. The technique was applied to a two-layered skin tissue phantom containing a 200- μm-diameter intralipid flow channel that features functional and morphological changes at the same time. Results show the potential for concurrent 3-D mapping of dynamic and static inhomogeneities in a highly scattering medium which can improve the contrast in non-invasive biological tissue imaging, providing a confocal image in addition to the Doppler flowmetry image.

Original languageEnglish
Article number8685137
Pages (from-to)6134-6140
Number of pages7
JournalIEEE Sensors Journal
Issue number15
Publication statusPublished - 1 Aug 2019


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