Don't panic. A guide to tryptophan depletion with disorder-specific anxiety provocation

S. D. Hood, C. J. Bell, S. V. Argyropoulos, D. J. Nutt

    Research output: Contribution to journalReview article

    Abstract

    The 2002 paper "Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine" by Bell and colleagues - reprinted in this issue of the Journal - reports on a study undertaken in the halcyon days of David Nutt's Psychopharmacology Unit at the University of Bristol, England. In this invited commentary authors of the original work discuss the impact of this paper on the field of acute tryptophan depletion research (especially in the field of clinical anxiety disorders) and the development of disorder-specific anxiogenic provocations over the past decade.

    Original languageEnglish
    Pages (from-to)1137-1140
    Number of pages4
    JournalJournal of Psychopharmacology
    Volume30
    Issue number11
    DOIs
    Publication statusPublished - 1 Nov 2016

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