Does Maternal Hypoglycemia during Screening Glucose Assessment Identify a Pregnancy At-Risk for Adverse Perinatal Outcome?

OBJECTIVE:To determine the perinatal outcome in pregnancies with maternalhypoglycemia following a second trimester oral glucose challenge test(GCT).STUDY DESIGN:Retrospective case–control study of pregnancies undergoing a secondtrimester 1-hour oral glucose challenge test (GCT). Hypoglycemicpregnancies (88 mg/dl. Antepartum, intrapartum, and neonatal outcomeswere assessed.RESULTS:Over 29 months, 334 hypoglycemic singleton pregnancies were matchedwith 334 controls. A greater number of special/neonatal intensive careunit (SCN/NICU) admissions occurred in the hypoglycemic group(48/334 (14.4%) vs 29/334 (8.7%) in the control group) (p¼0.02).The SCN/NICU admission rate remained after controlling for maternalhypertension, smoking, and preterm birth (p¼0.037). The developmentof pregnancy-induced hypertension in women with hypoglycemia 24/334 (7.2%) compared with euglycemic women 13/334 (3.9%, p