Do affective or dissociative symptoms mediate the association between childhood sexual trauma and transition to psychosis in an ultra-high risk cohort?

A. Thompson, S. Marwaha, B. Nelson, S.J. Wood, P.D. Mcgorry, A.R. Yung, Ashleigh Lin

Research output: Contribution to journalArticle

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Abstract

© 2016 Elsevier Ireland Ltd. We have previously reported an association between childhood sexual trauma and transition to psychosis in an Ultra High Risk (UHR) population. We aimed to investigate if this association was mediated by affective or dissociative symptoms. Data were from a large UHR for psychosis cohort study. None of the potential mediators (depression, anxiety, dissociation, mood swings and mania, assessed by the HAM-D, HAM-A and the CAARMS symptom scales) significantly mediated the total association between sexual abuse scores and transition. At the point of transition, the mechanistic pathway from sexual trauma to psychosis does not appear to operate through affective symptoms.
Original languageEnglish
Pages (from-to)182-185
Number of pages4
JournalPsychiatry Research
Volume236
Early online date8 Jan 2015
DOIs
Publication statusPublished - 28 Feb 2016

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Psychotic Disorders
Wounds and Injuries
Dissociative Disorders
Affective Symptoms
Sex Offenses
Bipolar Disorder
Ireland
Cohort Studies
Anxiety
Depression
Population

Cite this

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Do affective or dissociative symptoms mediate the association between childhood sexual trauma and transition to psychosis in an ultra-high risk cohort? / Thompson, A.; Marwaha, S.; Nelson, B.; Wood, S.J.; Mcgorry, P.D.; Yung, A.R.; Lin, Ashleigh.

In: Psychiatry Research, Vol. 236, 28.02.2016, p. 182-185.

Research output: Contribution to journalArticle

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AU - Thompson, A.

AU - Marwaha, S.

AU - Nelson, B.

AU - Wood, S.J.

AU - Mcgorry, P.D.

AU - Yung, A.R.

AU - Lin, Ashleigh

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AB - © 2016 Elsevier Ireland Ltd. We have previously reported an association between childhood sexual trauma and transition to psychosis in an Ultra High Risk (UHR) population. We aimed to investigate if this association was mediated by affective or dissociative symptoms. Data were from a large UHR for psychosis cohort study. None of the potential mediators (depression, anxiety, dissociation, mood swings and mania, assessed by the HAM-D, HAM-A and the CAARMS symptom scales) significantly mediated the total association between sexual abuse scores and transition. At the point of transition, the mechanistic pathway from sexual trauma to psychosis does not appear to operate through affective symptoms.

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