Divisions of labour in dendritic cell immune-surveillance and epigenetic mechanisms of immune evasion

Ben Christopher Wylie

    Research output: ThesisDoctoral Thesis

    460 Downloads (Pure)

    Abstract

    The recent clinical success of novel immunotherapies has brought into focus the potential of harnessing the Immune system to detect and destroy cancer cells. Dendritic cells are a specialised subset of immune cells that are critical for the initiation and regulation of anti-cancer Immunity. This thesis examines the role of unique subtypes of dendritic cells In the generation of immunity and investigates the development of resistance mechanisms, which allow cancers to escape immune-mediated destruction.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • The University of Western Australia
    Supervisors/Advisors
    • Waithman, Jason, Supervisor
    • Hart, Prudence, Supervisor
    • Cruickshank, Mark, Supervisor
    • Foley, Bree, Supervisor
    Thesis sponsors
    Award date29 Mar 2018
    DOIs
    Publication statusUnpublished - 2018

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