The recent clinical success of novel immunotherapies has brought into focus the potential of harnessing the Immune system to detect and destroy cancer cells. Dendritic cells are a specialised subset of immune cells that are critical for the initiation and regulation of anti-cancer Immunity. This thesis examines the role of unique subtypes of dendritic cells In the generation of immunity and investigates the development of resistance mechanisms, which allow cancers to escape immune-mediated destruction.
|Qualification||Doctor of Philosophy|
|Award date||29 Mar 2018|
|Publication status||Unpublished - 2018|