Disparity in implantable cardioverter defibrillator therapy among minority South Asians in the United Kingdom

Amar Mistry, Zakariyya Vali, Bharat Sidhu, Charley Budgeon, Matthew F. Yuyun, Vivetha Pooranachandran, Xin Li, Michelle Newton, Jamie Watts, Kamlesh Khunti, Nilesh J. Samani, G. Andre Ng

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective There are large geographical differences in implantable cardioverter defibrillator (ICD) implantation rates for reasons not completely understood. In an increasingly multiethnic population, we sought out to investigate whether ethnicity influenced ICD implantation rates. Methods This was a retrospective, cohort study of new ICD implantation or upgrade to ICD from January 2006 to February 2019 in recipients of Caucasian or South Asian ethnicity at a single tertiary centre in the UK. Data were obtained from a routinely collected local registry. Crude rates of ICD implantation were calculated for the population of Leicestershire county and were age-standardised to the UK population using the UK National Census of 2011. Results The Leicestershire population was 980 328 at the time of the Census, of which 761 403 (77.7%) were Caucasian and 155 500 (15.9%) were South Asian. Overall, 2650 ICD implantations were performed in Caucasian (91.9%) and South Asian (8.1%) patients. South Asians were less likely than Caucasians to receive an ICD (risk ratio (RR) 0.43, 95% CI 0.37 to 0.49, p<0.001) even when standardised for age (RR 0.75, 95% CI 0.74 to 0.75, p<0.001). This remained the case for primary prevention indication (age-standardised RR 0.91, 95% CI 0.90 to 0.91, p<0.001), while differences in secondary prevention ICD implants were even greater (age-standardised RR 0.49, 95% CI 0.48 to 0.50, p<0.001). Conclusion Despite a universal and free healthcare system, ICD implantation rates were significantly lower in the South Asian than the Caucasian population residing in the UK. Whether this is due to cultural acceptance or an unbalanced consideration is unclear.

Original languageEnglish
Pages (from-to)671-676
Number of pages6
JournalHeart
Volume106
Issue number9
DOIs
Publication statusPublished - 1 May 2020

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