Direct visualization of death of neurones projecting to specific targets in the developing rat brain

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    Abstract

    The fluorescent dye diamidino yellow was injected into parts of the developing visual and auditory systems in the rat. The dye was retrogradely transported by projecting neurones and was found to stain pyknotic profiles within the labelled cell populations. It is thus possible to visualize directly the death of neurones which project axons to specific and identified target regions within the nervous system.

    Original languageEnglish
    Pages (from-to)213-217
    Number of pages5
    JournalExperimental Brain Research
    Volume80
    Issue number1
    DOIs
    Publication statusPublished - 1 Apr 1990

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