Differences in blood pressure in infants after general anesthesia compared to awake regional anesthesia (GAS Study-A Prospective Randomized Trial)

M. E. McCann, D. E. Withington, S. J. Arnup, A. J. Davidson, N. Disma, G. Frawley, N. S. Morton, G. Bell, R. W. Hunt, D. C. Bellinger, D. M. Polaner, A. Leo, A. R. Absalom, B. S. von Ungern-Sternberg, F. Izzo, P. Szmuk, V. Young, S. G. Soriano, J. C. de Graaff

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    Abstract

    BACKGROUND: The General Anesthesia compared to Spinal anesthesia (GAS) study is a prospective randomized, controlled, multisite, trial designed to assess the influence of general anesthesia (GA) on neurodevelopment at 5 years of age. A secondary aim obtained from the blood pressure data of the GAS trial is to compare rates of intraoperative hypotension after anesthesia and to identify risk factors for intraoperative hypotension.

    METHODS: A total of 722 infants

    RESULTS: The relative risk of GA compared with RA predicting any measured hypotension of

    CONCLUSIONS: RA reduces the incidence of hypotension and the chance of intervention to treat it compared with sevoflurane anesthesia in young infants undergoing inguinal hernia repair.

    Original languageEnglish
    Pages (from-to)837-845
    Number of pages9
    JournalAnesthesia and Analgesia
    Volume125
    Issue number3
    DOIs
    Publication statusPublished - Sep 2017

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