TY - JOUR
T1 - Dexamethasone compared with betamethasone for glucocorticoid treatment of postpartum HELLP syndrome
AU - Isler, D.M.
AU - Magann, Pat
AU - Rinehard, B.K.
AU - Terrone, D.A.
AU - Bass, J.D.
AU - Martin, J.N.
PY - 2003
Y1 - 2003
N2 - Objectives: To compare the efficacy of dexamethasone and betamethasone to ameliorate the course of postpartum hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome. Methods: A prospective, mixed randomized/non-randomized clinical investigation of patients with postpartum HELLP syndrome. Treatment with either dexamethasone or betamethasone was continued until there was evidence of disease recovery. Results: Baseline characteristics of both the dexamethasone (n=18) and betamethasone (n=18) groups were similar. Although the time to discharge from the obstetrical recovery room was not statistically significant between groups, reduction in mean arterial blood pressure was more pronounced in the dexamethasone group as compared with the betamethasone group (−15.3±1.4 mmHg vs. −7.5±1.4 mmHg, respectively, P
AB - Objectives: To compare the efficacy of dexamethasone and betamethasone to ameliorate the course of postpartum hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome. Methods: A prospective, mixed randomized/non-randomized clinical investigation of patients with postpartum HELLP syndrome. Treatment with either dexamethasone or betamethasone was continued until there was evidence of disease recovery. Results: Baseline characteristics of both the dexamethasone (n=18) and betamethasone (n=18) groups were similar. Although the time to discharge from the obstetrical recovery room was not statistically significant between groups, reduction in mean arterial blood pressure was more pronounced in the dexamethasone group as compared with the betamethasone group (−15.3±1.4 mmHg vs. −7.5±1.4 mmHg, respectively, P
U2 - 10.1016/S0020-7292(02)00394-6
DO - 10.1016/S0020-7292(02)00394-6
M3 - Article
VL - 80
SP - 291
EP - 297
JO - International Journal of Gynecology Obstetrics
JF - International Journal of Gynecology Obstetrics
SN - 0020-6695
IS - 3
ER -