Development of immuno-flowFISH by imaging flow cytometry for the analysis of haematoligical maligancies

Research output: ThesisDoctoral Thesis

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Abstract

The outcome of my PhD is the development of a new invention for studying leukaemia. The method, called immuno-flowFISH, enables many thousand cells to be analysed to detect abnormal chromosomes. This invention is a world-first: it is automated, is more precise as only leukaemia cells are analysed and is 1,000-times more sensitive than established tests. Once I established the test, I evaluated its performance on chronic lymphocytic leukaemia, the commonest leukaemia in the western world. This confirmed its capability as a diagnostic test. The invention has been patented and won the ANSTO 2018 Eureka Prize for Innovative use of Technology.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Thesis sponsors
Award date30 Apr 2019
DOIs
Publication statusUnpublished - 2018

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