Development of a reliable and reproducible phantom manufacturing method using silica microspheres in silicone

Charlotte J. Maughan Jones, Peter R.T. Munro

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    3 Citations (Scopus)


    Optically scattering phantoms composed of silica microspheres embedded in an optically clear silicone matrix were manufactured using a previously developed method. Multiple problems, such as sphere aggregation, adsorption to the cast, and silicone shrinkage, were, however, frequently encountered. Solutions to these problems were developed and an improved method, incorporating these solutions, is presented. The improved method offers excellent reliability and reproducibility for creating phantoms with uniform scattering coefficient. We also present evidence of decreased sphere aggregation.

    Original languageEnglish
    Article number095004
    Number of pages5
    JournalJournal of Biomedical Optics
    Issue number9
    Publication statusPublished - 1 Sep 2017


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