Development of a cost-effective test system for measurement of vestibular evoked myogenic potentials (VEMPs)

Nor Haniza Abdul Wahat

Research output: ThesisDoctoral Thesis

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Abstract

[Truncated abstract] The present study aimed at developing a cost-effective, portable, robust and easily adaptable cervical vestibular evoked myogenic potentials (cVEMPs) and ocular vestibular evoked myogenic potentials (oVEMPs) recording system and protocol as a diagnostic tool and screening test for vestibular dysfunction. We modified both the standard recording electrode montages and the method of vestibular acoustic and mechanical stimulation to produce our process (introducing the 'palm-pulse' and 'finger-tap' methods). For cVEMPs, we recruited ten healthy adult subjects (seven for palm-pulse and three for finger-tap) and also two bilateral vestibular loss subjects for palm-pulse alone. For the finger-tap oVEMPs, we recruited ten healthy adults and five pathological subjects diagnosed with unilateral vestibular schwannoma. It was initially hypothesized that our electrode montages would produce similar responses as previously used montages. We also hypothesized that our longer acoustic 0.5 ms click stimulus would evoke similar VEMPs responses in the same way as the 0.1 ms click, if not better. We hypothesized that our methods of recording cVEMPs and oVEMPs would produce reliable and 'true' vestibular responses, uncontaminated by reflex responses from the neurons of the facial skin. We also hypothesized that our skull-tap process would evoke vestibular responses through their entire range of input-output function. Following the work of others, we also hypothesized that our palm-pulse and finger-tap stimuli would produce whole-head accelerations because of its directed impulse to the skull, and that our directed skull-tap stimulus to explicit stimulation sites on the skull would evoke responses from different hair cell groups of the left and right otolith organs. We found that our electrode montages produced acoustic cVEMPs and oVEMPs very similar to others who used different electrodes montages.
Original languageEnglish
QualificationDoctor of Philosophy
Publication statusUnpublished - 2010

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