Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events

F.G.R. Fowkes; G.D. Murray; I.G. Butcher; A.R. Folsom; A.T. Hirsch; D.J. Couper; G. Debacker; M.D. Kornitzer; A.B. Newman; K.C. Sutton-Tyrrell; M. Cushman; A.J. Lee; J.F. Price; R.B. D'Agostino; J.M. Murabito; Paul Norman; K.H. Masaki; L.M. Bouter; R.J. Heine; C.D.A.C. Stehouwer; M.M. Mcdermott; H.E.J.H.J. Stoffers; J.A. Knottnerus; M. Ögren; B. Hedblad; W. Koenig; C. Meisinger; J.A. Cauley; O.H. Franco; M.M.M. Hunink; A.F. Hofman; J.C.M. Witteman; M.H. Criqui; R.D. Langer; W.R. Hiatt; R.F. Hamman

doi:10.1177/2047487313516564

Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events

F.G.R. Fowkes, G.D. Murray, I.G. Butcher, A.R. Folsom, A.T. Hirsch, D.J. Couper, G. Debacker, M.D. Kornitzer, A.B. Newman, K.C. Sutton-Tyrrell, M. Cushman, A.J. Lee, J.F. Price, R.B. D'Agostino, J.M. Murabito, Paul Norman, K.H. Masaki, L.M. Bouter, R.J. Heine, C.D.A.C. StehouwerM.M. Mcdermott, H.E.J.H.J. Stoffers, J.A. Knottnerus, M. Ögren, B. Hedblad, W. Koenig, C. Meisinger, J.A. Cauley, O.H. Franco, M.M.M. Hunink, A.F. Hofman, J.C.M. Witteman, M.H. Criqui, R.D. Langer, W.R. Hiatt, R.F. Hamman

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Abstract

Background: The ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS. Design: An analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and were followed up for events. Methods: Subjects were divided into a development and internal validation dataset and an external validation dataset. Two models, comprising FRS and FRS+ABI, were fitted for the primary outcome of major coronary events. © 2013 The European Society of Cardiology.

Original language	English
Pages (from-to)	310-320
Journal	European Journal of Preventive Cardiology
Volume	21
Issue number	3
DOIs	https://doi.org/10.1177/2047487313516564
Publication status	Published - 2014

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Fowkes, F. G. R., Murray, G. D., Butcher, I. G., Folsom, A. R., Hirsch, A. T., Couper, D. J., Debacker, G., Kornitzer, M. D., Newman, A. B., Sutton-Tyrrell, K. C., Cushman, M., Lee, A. J., Price, J. F., D'Agostino, R. B., Murabito, J. M., Norman, P., Masaki, K. H., Bouter, L. M., Heine, R. J., ... Hamman, R. F. (2014). Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events. European Journal of Preventive Cardiology, 21(3), 310-320. https://doi.org/10.1177/2047487313516564

@article{a614e305db1540b098f024514bce113d,

title = "Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events",

abstract = "Background: The ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS. Design: An analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and were followed up for events. Methods: Subjects were divided into a development and internal validation dataset and an external validation dataset. Two models, comprising FRS and FRS+ABI, were fitted for the primary outcome of major coronary events. {\textcopyright} 2013 The European Society of Cardiology.",

author = "F.G.R. Fowkes and G.D. Murray and I.G. Butcher and A.R. Folsom and A.T. Hirsch and D.J. Couper and G. Debacker and M.D. Kornitzer and A.B. Newman and K.C. Sutton-Tyrrell and M. Cushman and A.J. Lee and J.F. Price and R.B. D'Agostino and J.M. Murabito and Paul Norman and K.H. Masaki and L.M. Bouter and R.J. Heine and C.D.A.C. Stehouwer and M.M. Mcdermott and H.E.J.H.J. Stoffers and J.A. Knottnerus and M. {\"O}gren and B. Hedblad and W. Koenig and C. Meisinger and J.A. Cauley and O.H. Franco and M.M.M. Hunink and A.F. Hofman and J.C.M. Witteman and M.H. Criqui and R.D. Langer and W.R. Hiatt and R.F. Hamman",

year = "2014",

doi = "10.1177/2047487313516564",

language = "English",

volume = "21",

pages = "310--320",

journal = "European Journal of Preventive Cardiology",

issn = "2047-4873",

publisher = "SAGE Publications Ltd",

number = "3",

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Fowkes, FGR, Murray, GD, Butcher, IG, Folsom, AR, Hirsch, AT, Couper, DJ, Debacker, G, Kornitzer, MD, Newman, AB, Sutton-Tyrrell, KC, Cushman, M, Lee, AJ, Price, JF, D'Agostino, RB, Murabito, JM, Norman, P, Masaki, KH, Bouter, LM, Heine, RJ, Stehouwer, CDAC, Mcdermott, MM, Stoffers, HEJHJ, Knottnerus, JA, Ögren, M, Hedblad, B, Koenig, W, Meisinger, C, Cauley, JA, Franco, OH, Hunink, MMM, Hofman, AF, Witteman, JCM, Criqui, MH, Langer, RD, Hiatt, WR & Hamman, RF 2014, 'Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events', European Journal of Preventive Cardiology, vol. 21, no. 3, pp. 310-320. https://doi.org/10.1177/2047487313516564

TY - JOUR

T1 - Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events

AU - Fowkes, F.G.R.

AU - Murray, G.D.

AU - Butcher, I.G.

AU - Folsom, A.R.

AU - Hirsch, A.T.

AU - Couper, D.J.

AU - Debacker, G.

AU - Kornitzer, M.D.

AU - Newman, A.B.

AU - Sutton-Tyrrell, K.C.

AU - Cushman, M.

AU - Lee, A.J.

AU - Price, J.F.

AU - D'Agostino, R.B.

AU - Murabito, J.M.

AU - Norman, Paul

AU - Masaki, K.H.

AU - Bouter, L.M.

AU - Heine, R.J.

AU - Stehouwer, C.D.A.C.

AU - Mcdermott, M.M.

AU - Stoffers, H.E.J.H.J.

AU - Knottnerus, J.A.

AU - Ögren, M.

AU - Hedblad, B.

AU - Koenig, W.

AU - Meisinger, C.

AU - Cauley, J.A.

AU - Franco, O.H.

AU - Hunink, M.M.M.

AU - Hofman, A.F.

AU - Witteman, J.C.M.

AU - Criqui, M.H.

AU - Langer, R.D.

AU - Hiatt, W.R.

AU - Hamman, R.F.

PY - 2014

Y1 - 2014

N2 - Background: The ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS. Design: An analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and were followed up for events. Methods: Subjects were divided into a development and internal validation dataset and an external validation dataset. Two models, comprising FRS and FRS+ABI, were fitted for the primary outcome of major coronary events. © 2013 The European Society of Cardiology.

AB - Background: The ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS. Design: An analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and were followed up for events. Methods: Subjects were divided into a development and internal validation dataset and an external validation dataset. Two models, comprising FRS and FRS+ABI, were fitted for the primary outcome of major coronary events. © 2013 The European Society of Cardiology.

U2 - 10.1177/2047487313516564

DO - 10.1177/2047487313516564

M3 - Article

C2 - 24367001

SN - 2047-4873

VL - 21

SP - 310

EP - 320

JO - European Journal of Preventive Cardiology

JF - European Journal of Preventive Cardiology

IS - 3

ER -

Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events

Abstract

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