Abstract
Ciprofloxacin has been shown to exhibit potent herbicidal activity through action against plant DNA gyrase, presenting a novel mode of action. Analogues of ciprofloxacin have been prepared with increased herbicidal activity and diminished antibacterial activity, compared to ciprofloxacin, as demonstrated using model systems.
| Language | English |
|---|---|
| Pages | 1869-1872 |
| Number of pages | 4 |
| Journal | Chemical Communications |
| Volume | 54 |
| Issue number | 15 |
| DOIs | |
| Publication status | Published - 21 Feb 2018 |
Cite this
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Developing ciprofloxacin analogues against plant DNA gyrase : a novel herbicide mode of action. / Wallace, Michael D.; Waraich, Nidda F.; Debowski, Aleksandra W.; Corral, Maxime G.; Maxwell, Anthony; Mylne, Joshua S.; Stubbs, Keith A.
In: Chemical Communications, Vol. 54, No. 15, 21.02.2018, p. 1869-1872.Research output: Contribution to journal › Article
TY - JOUR
T1 - Developing ciprofloxacin analogues against plant DNA gyrase
T2 - Chemical Communications, 2000
AU - Wallace, Michael D.
AU - Waraich, Nidda F.
AU - Debowski, Aleksandra W.
AU - Corral, Maxime G.
AU - Maxwell, Anthony
AU - Mylne, Joshua S.
AU - Stubbs, Keith A.
PY - 2018/2/21
Y1 - 2018/2/21
N2 - Ciprofloxacin has been shown to exhibit potent herbicidal activity through action against plant DNA gyrase, presenting a novel mode of action. Analogues of ciprofloxacin have been prepared with increased herbicidal activity and diminished antibacterial activity, compared to ciprofloxacin, as demonstrated using model systems.
AB - Ciprofloxacin has been shown to exhibit potent herbicidal activity through action against plant DNA gyrase, presenting a novel mode of action. Analogues of ciprofloxacin have been prepared with increased herbicidal activity and diminished antibacterial activity, compared to ciprofloxacin, as demonstrated using model systems.
KW - ARABIDOPSIS-THALIANA
KW - EVOLUTION
U2 - 10.1039/c7cc09518j
DO - 10.1039/c7cc09518j
M3 - Article
VL - 54
SP - 1869
EP - 1872
JO - Chemical Communications, 2000
JF - Chemical Communications, 2000
SN - 1359-7345
IS - 15
ER -