Developing ciprofloxacin analogues against plant DNA gyrase: a novel herbicide mode of action

Michael D. Wallace, Nidda F. Waraich, Aleksandra W. Debowski, Maxime G. Corral, Anthony Maxwell, Joshua S. Mylne, Keith A. Stubbs

Research output: Contribution to journalArticle

6 Citations (Scopus)


Ciprofloxacin has been shown to exhibit potent herbicidal activity through action against plant DNA gyrase, presenting a novel mode of action. Analogues of ciprofloxacin have been prepared with increased herbicidal activity and diminished antibacterial activity, compared to ciprofloxacin, as demonstrated using model systems.

Original languageEnglish
Pages (from-to)1869-1872
Number of pages4
JournalChemical Communications
Issue number15
Publication statusPublished - 21 Feb 2018

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