Developing algorithms to improve predicting the development of and screening for gestational diabetes mellitus in rural communities

Research output: ThesisDoctoral Thesis

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Abstract

Hyperglycaemia in pregnancy (HIP) increases the risk for adverse birth outcomes and predisposes mothers and babies to future chronic metabolic disease. This thesis demonstrates that screening for HIP using an oral glucose tolerance test (OGTT) is a poor fit for rural and remote healthcare settings; the OGTT is inaccurate and uptake is inadequate. Improved screening algorithms using glycated haemoglobin (before 20 weeks gestation) and fasting plasma glucose (after 24 weeks gestation)have the potential to improve screening coverage; expedite detection of the HIP; reduce the burden of OGTT, and improve birth outcomes. These improvements will be critical to reducing the significant intergenerational impact of the HIP.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • Marley, Julia, Supervisor
  • Atkinson, David, Supervisor
  • Tanner, Melissa, Supervisor, External person
Thesis sponsors
Award date29 Jun 2022
DOIs
Publication statusUnpublished - 2021

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