Detecting Fetal Macrosomia with Abdominal Circumference Alone

C. Henrichs, Pat Magann, K.L. Grantley, J.H. Crews, M. Sanderson, S.P. Chauhan

    Research output: Contribution to journalArticle

    18 Citations (Scopus)

    Abstract

    OBJECTIVE: To determine if abdominal circumference (AC) can identify macrosomia (greater than or equal to4,000 g) at or beyond 37 weeks.STUDY DESIGN: Prospectively, parturients at term admitted for delivery underwent sonographic mensuration of AC. A receiver-operating characteristic (ROC) curve was constructed to determine if AC can differentiate between normal (birth weight < 3,999 g) and macrosomia. A likelihood ratio was calculated. P <.05 was considered significant.RESULTS: The mean gestational age of the 256 subjects was 39.1 +/- 1.5 weeks, and the prevalence of macrosomia was 8.2% (21/256). Inspection of the ROC curve indicated that ACgreater than or equal to350 mm can identify macrosomic fetuses. The area tinder the ROC curve (0.79 +/- 0.04 for macrosomia) was significantly different than the area under the nondiagnostic line (P <.005). The likelihood ratio for AC to detect macrosomia was 2.9 (95% confidence interval, 2.1-4.0). Based on the proportion of macrosomia in our population, we would require over 1,000,000 newborns for a macrosomia analysis to obtain narrow confidence intervals around a clinically useful likelihood ratio.CONCLUSION: Using the guidelines proposed by the Evidence-Based Medicine Working Group, AC is slightly useful in detecting macrosomia among term parturients.
    Original languageEnglish
    Pages (from-to)339-342
    JournalJournal of Reproductive Medicine
    Volume48
    Issue number5
    Publication statusPublished - 2003

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    Fetal Macrosomia
    ROC Curve
    Parturition
    Confidence Intervals
    Evidence-Based Medicine
    Birth Weight
    Gestational Age
    Fetus
    Guidelines
    Population

    Cite this

    Henrichs, C., Magann, P., Grantley, K. L., Crews, J. H., Sanderson, M., & Chauhan, S. P. (2003). Detecting Fetal Macrosomia with Abdominal Circumference Alone. Journal of Reproductive Medicine, 48(5), 339-342.
    Henrichs, C. ; Magann, Pat ; Grantley, K.L. ; Crews, J.H. ; Sanderson, M. ; Chauhan, S.P. / Detecting Fetal Macrosomia with Abdominal Circumference Alone. In: Journal of Reproductive Medicine. 2003 ; Vol. 48, No. 5. pp. 339-342.
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    abstract = "OBJECTIVE: To determine if abdominal circumference (AC) can identify macrosomia (greater than or equal to4,000 g) at or beyond 37 weeks.STUDY DESIGN: Prospectively, parturients at term admitted for delivery underwent sonographic mensuration of AC. A receiver-operating characteristic (ROC) curve was constructed to determine if AC can differentiate between normal (birth weight < 3,999 g) and macrosomia. A likelihood ratio was calculated. P <.05 was considered significant.RESULTS: The mean gestational age of the 256 subjects was 39.1 +/- 1.5 weeks, and the prevalence of macrosomia was 8.2{\%} (21/256). Inspection of the ROC curve indicated that ACgreater than or equal to350 mm can identify macrosomic fetuses. The area tinder the ROC curve (0.79 +/- 0.04 for macrosomia) was significantly different than the area under the nondiagnostic line (P <.005). The likelihood ratio for AC to detect macrosomia was 2.9 (95{\%} confidence interval, 2.1-4.0). Based on the proportion of macrosomia in our population, we would require over 1,000,000 newborns for a macrosomia analysis to obtain narrow confidence intervals around a clinically useful likelihood ratio.CONCLUSION: Using the guidelines proposed by the Evidence-Based Medicine Working Group, AC is slightly useful in detecting macrosomia among term parturients.",
    author = "C. Henrichs and Pat Magann and K.L. Grantley and J.H. Crews and M. Sanderson and S.P. Chauhan",
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    Henrichs, C, Magann, P, Grantley, KL, Crews, JH, Sanderson, M & Chauhan, SP 2003, 'Detecting Fetal Macrosomia with Abdominal Circumference Alone' Journal of Reproductive Medicine, vol. 48, no. 5, pp. 339-342.

    Detecting Fetal Macrosomia with Abdominal Circumference Alone. / Henrichs, C.; Magann, Pat; Grantley, K.L.; Crews, J.H.; Sanderson, M.; Chauhan, S.P.

    In: Journal of Reproductive Medicine, Vol. 48, No. 5, 2003, p. 339-342.

    Research output: Contribution to journalArticle

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    AU - Henrichs, C.

    AU - Magann, Pat

    AU - Grantley, K.L.

    AU - Crews, J.H.

    AU - Sanderson, M.

    AU - Chauhan, S.P.

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    N2 - OBJECTIVE: To determine if abdominal circumference (AC) can identify macrosomia (greater than or equal to4,000 g) at or beyond 37 weeks.STUDY DESIGN: Prospectively, parturients at term admitted for delivery underwent sonographic mensuration of AC. A receiver-operating characteristic (ROC) curve was constructed to determine if AC can differentiate between normal (birth weight < 3,999 g) and macrosomia. A likelihood ratio was calculated. P <.05 was considered significant.RESULTS: The mean gestational age of the 256 subjects was 39.1 +/- 1.5 weeks, and the prevalence of macrosomia was 8.2% (21/256). Inspection of the ROC curve indicated that ACgreater than or equal to350 mm can identify macrosomic fetuses. The area tinder the ROC curve (0.79 +/- 0.04 for macrosomia) was significantly different than the area under the nondiagnostic line (P <.005). The likelihood ratio for AC to detect macrosomia was 2.9 (95% confidence interval, 2.1-4.0). Based on the proportion of macrosomia in our population, we would require over 1,000,000 newborns for a macrosomia analysis to obtain narrow confidence intervals around a clinically useful likelihood ratio.CONCLUSION: Using the guidelines proposed by the Evidence-Based Medicine Working Group, AC is slightly useful in detecting macrosomia among term parturients.

    AB - OBJECTIVE: To determine if abdominal circumference (AC) can identify macrosomia (greater than or equal to4,000 g) at or beyond 37 weeks.STUDY DESIGN: Prospectively, parturients at term admitted for delivery underwent sonographic mensuration of AC. A receiver-operating characteristic (ROC) curve was constructed to determine if AC can differentiate between normal (birth weight < 3,999 g) and macrosomia. A likelihood ratio was calculated. P <.05 was considered significant.RESULTS: The mean gestational age of the 256 subjects was 39.1 +/- 1.5 weeks, and the prevalence of macrosomia was 8.2% (21/256). Inspection of the ROC curve indicated that ACgreater than or equal to350 mm can identify macrosomic fetuses. The area tinder the ROC curve (0.79 +/- 0.04 for macrosomia) was significantly different than the area under the nondiagnostic line (P <.005). The likelihood ratio for AC to detect macrosomia was 2.9 (95% confidence interval, 2.1-4.0). Based on the proportion of macrosomia in our population, we would require over 1,000,000 newborns for a macrosomia analysis to obtain narrow confidence intervals around a clinically useful likelihood ratio.CONCLUSION: Using the guidelines proposed by the Evidence-Based Medicine Working Group, AC is slightly useful in detecting macrosomia among term parturients.

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    Henrichs C, Magann P, Grantley KL, Crews JH, Sanderson M, Chauhan SP. Detecting Fetal Macrosomia with Abdominal Circumference Alone. Journal of Reproductive Medicine. 2003;48(5):339-342.