Detecting familial hypercholesterolaemia in the community: Impact of a telephone call from a chemical pathologist to the requesting general practitioner

Damon Bell, Amanda Hooper, G.A. Edwards, Lynda Southwell, Jing Pang, Frank Van Bockxmeer, Gerald Watts, John Burnett

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

Objective: To determine whether a telephone call from a chemical pathologist to the requesting general practitioner (GP) of individuals at high risk of familial hypercholesterolaemia (FH) increases specialist referral and detection of FH. Method: Individuals with an LDL-cholesterol ≥6.5mmol/L without secondary causes were identified from a community laboratory; 100 cases and 96 historical controls. All laboratory reports (cases and controls) received interpretative comments highlighting FH. In addition, the cases' GPs received a telephone call from the chemical pathologist to highlight their patient's risk of FH and suggest specialist referral, whereas with the controls' GPs were not telephoned. Results: After 12 months follow-up, 27 (27%) cases were referred to clinic compared with 4 (4%) controls (p
Original languageEnglish
Pages (from-to)469-472
JournalAtherosclerosis
Volume234
Issue number2
DOIs
Publication statusPublished - 2014

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