Depressive symptoms, body composition and bone mass in young adults: a prospective cohort study

K. Zhu, K. Allen, J. Mountain, S. Lye, C. Pennell, J. P. Walsh

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)
379 Downloads (Pure)


Background:An association between depression and obesity is well recognised, but longitudinal studies of depressive symptoms in adolescents as a predictor of body composition are lacking.Objective:We examined depressive symptoms at age 14, 17 and 20 years as predictors of lean, fat and bone mass at age 20 years in a birth cohort.Subjects/methods:In 1161 participants (569 females) in the Western Australia Pregnancy Cohort (Raine) Study, depressive symptoms were assessed using the Beck Depression Inventory for Youth at age 14 and 17 years, and the Depression, Anxiety and Stress Scale 21 at age 20 years. Participants were further classified into two trajectories using latent class analysis: no/transient and persistent/recurrent depression. At age 20 years, lean body mass (LBM), fat body mass (FBM) and total body bone mass were measured by dual-energy X-ray absorptiometry.Results:In females, accounting for age and lifestyle factors, depression scores at age 14 and 20 years were positively associated with body weight, body mass index (BMI), FBM and % FBM (r=0.110–0.184, P-2), FBM (+3.9 kg) and % FBM (+2.2%) and significantly lower % LBM (−2.2%) at age 20 years than those with no/transient depression (n=470; all P

Original languageEnglish
Pages (from-to)576–581
Number of pages6
JournalInternational Journal of Obesity
Issue number4
Early online date20 Dec 2016
Publication statusPublished - 1 Apr 2017


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