Dengue: A Minireview

Harapan Harapan, Alice Michie, R. Tedjo Sasmono, Allison Imrie

Research output: Contribution to journalReview article

Abstract

Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a mosquito-borne disease of major public health concern associated with significant morbidity, mortality, and economic cost, particularly in developing countries. Dengue incidence has increased 30-fold in the last 50 years and over 50% of the world's population, in more than 100 countries, live in areas at risk of DENV infection. We reviews DENV biology, epidemiology, transmission dynamics including circulating serotypes and genotypes, the immune response, the pathogenesis of the disease as well as updated diagnostic methods, treatments, vector control and vaccine developments.

Original languageEnglish
JournalViruses
Volume12
Issue number8
DOIs
Publication statusPublished - 30 Jul 2020

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    Harapan, H., Michie, A., Sasmono, R. T., & Imrie, A. (2020). Dengue: A Minireview. Viruses, 12(8). https://doi.org/10.3390/v12080829