Demographics of polycystic kidney disease and captive population viability in pygmy hippopotamus (Choeropsis liberiensis)

Gabriella L. Flacke, Joseph L. Tomkins, Robert Black, Beatrice Steck

    Research output: Contribution to journalArticle

    1 Citation (Scopus)

    Abstract

    Polycystic kidney disease (PKD) was previously diagnosed at necropsy in several pygmy hippopotami (Choeropsis liberiensis) from the Smithsonian National Zoo and Zoo Basel, suggesting a threat to the long-term viability of the captive population. We determined the incidence and demographics of PKD in the captive population historically; we tested if the condition is linked to pedigree; we investigated mode of inheritance; we examined effects of PKD on longevity; we conducted survival analysis; and we examined long-term population viability. Thirty-seven percent of 149 necropsied adult pygmy hippos were affected by PKD, and it was more common in females, controlling for the overall female-biased sex-ratio. Prevalence increased significantly with age, but most hippos were beyond their reproductive prime before developing clinical signs; thus fecundity was likely unaffected. PKD was linked to pedigree and may exhibit X-linked dominance, but further research is needed to definitively establish the mode of inheritance. PKD did not affect longevity, overall or within any age class. There was no significant correlation between inbreeding coefficient (F) and PKD, and the prevalence in wild-caught and captive-born animals was similar. Longevity for both captive-born and inbred hippos (F > 0) was significantly shorter than longevity for their wild-caught and non-inbred counterparts. Demographic projections indicated the extant population will likely experience a slow increase over time, provided there are no space constraints. We conclude that although PKD is an important cause of morbidity and mortality in pygmy hippos, the condition is not a primary concern for overall viability of the captive population.

    Original languageEnglish
    Pages (from-to)136-151
    Number of pages16
    JournalZoo Biology
    Volume36
    Issue number2
    DOIs
    Publication statusPublished - 1 Mar 2017

    Fingerprint

    demographic statistics
    viability
    zoos
    pedigree
    inheritance (genetics)
    polycystic kidney diseases
    Hexaprotodon liberiensis
    inbreeding coefficient
    dominance (genetics)
    age structure
    morbidity
    necropsy
    sex ratio
    fecundity
    incidence
    animals

    Cite this

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    abstract = "Polycystic kidney disease (PKD) was previously diagnosed at necropsy in several pygmy hippopotami (Choeropsis liberiensis) from the Smithsonian National Zoo and Zoo Basel, suggesting a threat to the long-term viability of the captive population. We determined the incidence and demographics of PKD in the captive population historically; we tested if the condition is linked to pedigree; we investigated mode of inheritance; we examined effects of PKD on longevity; we conducted survival analysis; and we examined long-term population viability. Thirty-seven percent of 149 necropsied adult pygmy hippos were affected by PKD, and it was more common in females, controlling for the overall female-biased sex-ratio. Prevalence increased significantly with age, but most hippos were beyond their reproductive prime before developing clinical signs; thus fecundity was likely unaffected. PKD was linked to pedigree and may exhibit X-linked dominance, but further research is needed to definitively establish the mode of inheritance. PKD did not affect longevity, overall or within any age class. There was no significant correlation between inbreeding coefficient (F) and PKD, and the prevalence in wild-caught and captive-born animals was similar. Longevity for both captive-born and inbred hippos (F > 0) was significantly shorter than longevity for their wild-caught and non-inbred counterparts. Demographic projections indicated the extant population will likely experience a slow increase over time, provided there are no space constraints. We conclude that although PKD is an important cause of morbidity and mortality in pygmy hippos, the condition is not a primary concern for overall viability of the captive population.",
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    Demographics of polycystic kidney disease and captive population viability in pygmy hippopotamus (Choeropsis liberiensis). / Flacke, Gabriella L.; Tomkins, Joseph L.; Black, Robert; Steck, Beatrice.

    In: Zoo Biology, Vol. 36, No. 2, 01.03.2017, p. 136-151.

    Research output: Contribution to journalArticle

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