Demographic and Clinical Predictors of Trait Impulsivity in Parkinson's Disease Patients

Maddeson Riley, Megan Bakeberg, Michelle Byrnes, Alexa Jefferson, Soumya Ghosh, Rick Stell, Frank L. Mastaglia, Dana Hince, Ryan S. Anderton

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background. Impulsive behaviour has become increasingly recognised as a neuropsychiatric complication of Parkinson's disease (PD). Thought to be a product of compromised cognitive control, the spectrum of impulsive behaviours in PD ranges from cognitive disinhibition to impulse control disorders (ICDs). Objective. At present, there are no indicators for trait impulsivity in PD. The objective of the current study was to identify demographic and clinical predictors of susceptibility to trait impulsivity in a cohort of PD patients. Methods. The current study assessed impulsivity using the Barratt Impulsiveness Scale 11 (BIS-11) in a cohort of 87 PD patients. General linear models (GLMs) were used to identify clinical and demographic variables predictive of heightened BIS-11 second-order attentional and nonplanning subscale scores. Results. Male gender, no history of smoking, postsecondary education, and heightened disease severity were predictive of increased BIS-11 attentional scores (p <0.05). Similarly, male gender, after secondary education, and disease severity were predictive of increased BIS-11 nonplanning scores (p <0.05). Contrary to previous reports, dopaminergic medication use was not a significant determinant of either BIS-11 subscale scores. Conclusions. Several demographic and clinical variables including male gender, no history of past smoking, after secondary education, and elevated disease severity are associated with impulsivity in PD.

Original languageEnglish
Article number9472120
Number of pages7
JournalParkinson's Disease
Volume2018
DOIs
Publication statusPublished - 2018

Cite this

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title = "Demographic and Clinical Predictors of Trait Impulsivity in Parkinson's Disease Patients",
abstract = "Background. Impulsive behaviour has become increasingly recognised as a neuropsychiatric complication of Parkinson's disease (PD). Thought to be a product of compromised cognitive control, the spectrum of impulsive behaviours in PD ranges from cognitive disinhibition to impulse control disorders (ICDs). Objective. At present, there are no indicators for trait impulsivity in PD. The objective of the current study was to identify demographic and clinical predictors of susceptibility to trait impulsivity in a cohort of PD patients. Methods. The current study assessed impulsivity using the Barratt Impulsiveness Scale 11 (BIS-11) in a cohort of 87 PD patients. General linear models (GLMs) were used to identify clinical and demographic variables predictive of heightened BIS-11 second-order attentional and nonplanning subscale scores. Results. Male gender, no history of smoking, postsecondary education, and heightened disease severity were predictive of increased BIS-11 attentional scores (p <0.05). Similarly, male gender, after secondary education, and disease severity were predictive of increased BIS-11 nonplanning scores (p <0.05). Contrary to previous reports, dopaminergic medication use was not a significant determinant of either BIS-11 subscale scores. Conclusions. Several demographic and clinical variables including male gender, no history of past smoking, after secondary education, and elevated disease severity are associated with impulsivity in PD.",
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author = "Maddeson Riley and Megan Bakeberg and Michelle Byrnes and Alexa Jefferson and Soumya Ghosh and Rick Stell and Mastaglia, {Frank L.} and Dana Hince and Anderton, {Ryan S.}",
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Demographic and Clinical Predictors of Trait Impulsivity in Parkinson's Disease Patients. / Riley, Maddeson; Bakeberg, Megan; Byrnes, Michelle; Jefferson, Alexa; Ghosh, Soumya; Stell, Rick; Mastaglia, Frank L.; Hince, Dana; Anderton, Ryan S.

In: Parkinson's Disease, Vol. 2018, 9472120, 2018.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Demographic and Clinical Predictors of Trait Impulsivity in Parkinson's Disease Patients

AU - Riley, Maddeson

AU - Bakeberg, Megan

AU - Byrnes, Michelle

AU - Jefferson, Alexa

AU - Ghosh, Soumya

AU - Stell, Rick

AU - Mastaglia, Frank L.

AU - Hince, Dana

AU - Anderton, Ryan S.

PY - 2018

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N2 - Background. Impulsive behaviour has become increasingly recognised as a neuropsychiatric complication of Parkinson's disease (PD). Thought to be a product of compromised cognitive control, the spectrum of impulsive behaviours in PD ranges from cognitive disinhibition to impulse control disorders (ICDs). Objective. At present, there are no indicators for trait impulsivity in PD. The objective of the current study was to identify demographic and clinical predictors of susceptibility to trait impulsivity in a cohort of PD patients. Methods. The current study assessed impulsivity using the Barratt Impulsiveness Scale 11 (BIS-11) in a cohort of 87 PD patients. General linear models (GLMs) were used to identify clinical and demographic variables predictive of heightened BIS-11 second-order attentional and nonplanning subscale scores. Results. Male gender, no history of smoking, postsecondary education, and heightened disease severity were predictive of increased BIS-11 attentional scores (p <0.05). Similarly, male gender, after secondary education, and disease severity were predictive of increased BIS-11 nonplanning scores (p <0.05). Contrary to previous reports, dopaminergic medication use was not a significant determinant of either BIS-11 subscale scores. Conclusions. Several demographic and clinical variables including male gender, no history of past smoking, after secondary education, and elevated disease severity are associated with impulsivity in PD.

AB - Background. Impulsive behaviour has become increasingly recognised as a neuropsychiatric complication of Parkinson's disease (PD). Thought to be a product of compromised cognitive control, the spectrum of impulsive behaviours in PD ranges from cognitive disinhibition to impulse control disorders (ICDs). Objective. At present, there are no indicators for trait impulsivity in PD. The objective of the current study was to identify demographic and clinical predictors of susceptibility to trait impulsivity in a cohort of PD patients. Methods. The current study assessed impulsivity using the Barratt Impulsiveness Scale 11 (BIS-11) in a cohort of 87 PD patients. General linear models (GLMs) were used to identify clinical and demographic variables predictive of heightened BIS-11 second-order attentional and nonplanning subscale scores. Results. Male gender, no history of smoking, postsecondary education, and heightened disease severity were predictive of increased BIS-11 attentional scores (p <0.05). Similarly, male gender, after secondary education, and disease severity were predictive of increased BIS-11 nonplanning scores (p <0.05). Contrary to previous reports, dopaminergic medication use was not a significant determinant of either BIS-11 subscale scores. Conclusions. Several demographic and clinical variables including male gender, no history of past smoking, after secondary education, and elevated disease severity are associated with impulsivity in PD.

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